Ignite Creation Date:
2024-05-06 @ 2:36 PM
Last Modification Date:
2024-10-26 @ 1:33 PM
Study NCT ID:
NCT04364217
Status:
RECRUITING
Last Update Posted:
2023-03-02
First Post:
2020-03-06
Brief Title:
Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser
Sponsor:
Massachusetts General Hospital
Organization:
Massachusetts General Hospital
Study Overview
Official Title:
Evaluating the Mechanism of Pain and Itch Reduction in Burn Scars Following Fractional Ablative CO2 Laser Treatment
Status:
RECRUITING
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hypertrophic Burn Scars HTBS are often treated with Fractional CO2 laser therapy to improve cosmetic appearance It has been noted that this leads to a reduction in the pain and itch associated with this type of scars While this phenomenon is commonly described in the literature the mechanism of pain and itch reduction in unclear The investigators aim to better understand this process by histological evaluation of HTBS at different stages of laser treatment
Detailed Description:
During our study patients with painful andor itchy burn scars will undergo standard treatment with fractional CO2 laser In addition to the standard of care treatment participants will undergo skin biopsies and be asked to complete Patient Reported Outcome Measure questionnaires related to their HTBS Burn scars will also undergo standard and 3 dimensional photography at the different stages of treatment Biopsy samples will undergo various staining techniques to establish the changes in tissue that occur with the laser treatment This information will also be correlated with the symptomatic changes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None