Ignite Creation Date:
2024-05-05 @ 5:08 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00392912
Status:
COMPLETED
Last Update Posted:
2010-08-19
First Post:
2006-10-24
Brief Title:
Effect of Testosterone Therapy in Men With Alzheimers Disease and Low Testosterone
Sponsor:
Michael E DeBakey VA Medical Center
Organization:
Michael E DeBakey VA Medical Center
Study Overview
Official Title:
A Pilot Study of the Effect of Testosterone on Cerebral Glucose Metabolism in Hypogonadal Males With Alzheimers Disease
Status:
COMPLETED
Status Verified Date:
2010-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Treatment with testosterone can improve performance on tests of spatial ability in men with low testosterone levels and Alzheimers disease Improved performance on these tests may mean an improved ability to get around in ones environment without getting lost or injured This could have a positive impact on both patients and those who care for them We will investigate what areas of the brain are involved in these improvements in spatial ability This will be done using a PET scan which creates a 3-dimensional image of the brain that can allow us to see how the brain functions
Detailed Description:
Volunteers will be treated with a prescription testosterone gel applied to the shoulder or other body area each day This treatment will continue for 6 months Subjects will undergo a PET scan at the beginning of the study and after approximately 2 months of treatment Subjects will undergo some cognitive testing throughout the study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None