Ignite Creation Date:
2024-05-05 @ 5:11 PM
Last Modification Date:
2024-10-26 @ 9:28 AM
Study NCT ID:
NCT00400036
Status:
COMPLETED
Last Update Posted:
2006-11-16
First Post:
2006-11-14
Brief Title:
Dietary Fish Protein in Subjects With Insulin Resistance
Sponsor:
Laval University
Organization:
Laval University
Study Overview
Official Title:
Assessment of Insulin Sensitivity in Insulin-Resistant Subjects Fed Fish Protein
Status:
COMPLETED
Status Verified Date:
2006-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The objective of our research project is to determine the effects of fish protein present in fish on insulin sensitivity in insulin-resistant human individuals and its mechanism of action on glucose metabolism Our hypothesis is that fish protein improves insulin sensitivity glucose tolerance and plasma lipid profile through an improvement in a primary defect in insulin signaling in overweight and insulin-resistant subjects
Detailed Description:
Recent data show that cod protein prevents the development of insulin resistance in rats Dietary fish protein may also enhance insulin sensitivity in overweight insulin-resistant subjects by improving a primary defect in insulin signaling to PI 3-kinase leading to reduced activation of the downstream effectors Akt and PKC To determine whether this is the case we will study the effects of fish protein on insulin sensitivity in humans and how it improves the ability of muscles to use glucose Such studies will help to advise individuals with insulin resistance or type 2 diabetes about eating fish
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None