Ignite Creation Date:
2024-05-05 @ 5:14 PM
Last Modification Date:
2024-10-26 @ 9:29 AM
Study NCT ID:
NCT00413140
Status:
COMPLETED
Last Update Posted:
2006-12-19
First Post:
2006-12-18
Brief Title:
Non-Invasive Biomarkers in Cystic Fibrosis
Sponsor:
Maastricht University Medical Center
Organization:
Maastricht University Medical Center
Study Overview
Official Title:
Biomarkers in Exhaled Breath Indicate Presence Control and Severity of Cystic Fibrosis
Status:
COMPLETED
Status Verified Date:
2003-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background Chronic airway inflammation is present in cystic fibrosis Non-invasive inflammometry may be useful in disease management
Objective We studied 1 the ability of fractional exhaled nitric oxide and inflammatory markers acidity nitrite nitrate hydrogen peroxide 8-isoprostane interferon-γ tumor necrosis factor-α interleukin-2-4-5-10 in exhaled breath condensate to discriminate between cystic fibrosis and control children and 2 the relationship of biomarkers with control and severity of cystic fibrosis
Methods In 98 children 48 cystic fibrosis 50 controls condensate was collected using a glass condenser Exhaled nitric oxide was measured using the NIOX
Objective We studied 1 the ability of fractional exhaled nitric oxide and inflammatory markers acidity nitrite nitrate hydrogen peroxide 8-isoprostane interferon-γ tumor necrosis factor-α interleukin-2-4-5-10 in exhaled breath condensate to discriminate between cystic fibrosis and control children and 2 the relationship of biomarkers with control and severity of cystic fibrosis
Methods In 98 children 48 cystic fibrosis 50 controls condensate was collected using a glass condenser Exhaled nitric oxide was measured using the NIOX
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None