Ignite Creation Date:
2024-05-05 @ 5:15 PM
Last Modification Date:
2024-10-26 @ 9:29 AM
Study NCT ID:
NCT00415896
Status:
UNKNOWN
Last Update Posted:
2006-12-25
First Post:
2006-12-22
Brief Title:
Impact of Respiratory Muscle Unloading on Respiratory Muscle Endurance
Sponsor:
Krankenhaus Kloster Grafschaft
Organization:
Krankenhaus Kloster Grafschaft
Study Overview
Official Title:
Impact of Respiratory Muscle Unloading on Respiratory Muscle Endurance
Status:
UNKNOWN
Status Verified Date:
2006-12
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study investigates how different degrees of muscular unloading during mechanical ventilation impact endurance of succeeding spontaneous breathing trials
Detailed Description:
Liberation from mechanical ventilation in difficult to wean patients is best accomplished by intermittent spontaneous breathing trials 1 Optimal respiratory muscle rest in-between breathing trials however has never been investigated
Using a crossover design patients are to be ventilated with complete and partial respiratory muscle unloading for a period of ten hours respectively Respiratory muscle activity is being monitored by oesophageal balloon technique using a commercially available System Avea Viasys Conshohocken PA USA Time of spontaneous breathing respiratory- and ABG parameters are being determined to characterize the course of each spontaneous breathing trial
References
1 Esteban A F Frutos M J Tobin I Alia J F Solsona I Valverdu R Fernandez M A de la Cal S Benito R Tomas and et al 1995 A comparison of four methods of weaning patients from mechanical ventilation Spanish Lung Failure Collaborative Group N Engl J Med 3326345-50
Using a crossover design patients are to be ventilated with complete and partial respiratory muscle unloading for a period of ten hours respectively Respiratory muscle activity is being monitored by oesophageal balloon technique using a commercially available System Avea Viasys Conshohocken PA USA Time of spontaneous breathing respiratory- and ABG parameters are being determined to characterize the course of each spontaneous breathing trial
References
1 Esteban A F Frutos M J Tobin I Alia J F Solsona I Valverdu R Fernandez M A de la Cal S Benito R Tomas and et al 1995 A comparison of four methods of weaning patients from mechanical ventilation Spanish Lung Failure Collaborative Group N Engl J Med 3326345-50
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None