Ignite Creation Date:
2024-05-05 @ 5:15 PM
Last Modification Date:
2024-10-26 @ 9:29 AM
Study NCT ID:
NCT00417664
Status:
COMPLETED
Last Update Posted:
2022-05-27
First Post:
2007-01-03
Brief Title:
Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients
Sponsor:
Stanford University
Organization:
Stanford University
Study Overview
Official Title:
ICU Delirium Can Dexmedetomidine Reduce Its Incidence
Status:
COMPLETED
Status Verified Date:
2022-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this chart review study is to determine whether the use of dexmedetomidine a selective α2-adrenergic receptor agonist with sedative analgesic and antinociceptive properties would be associated with a lower incidence of delirium when compared to propofol and midazolam We hypothesize that sedation with dexmedetomidine following cardiac surgery with CPB will be associated with a lower incidence of postoperative delirium
Detailed Description:
Delirium is the most common psychiatric syndrome found in the general hospital setting Between 32 - 80 of cardiac surgery patients may experience post-operative delirium Because failure to recognize delirium leads to increased morbidity and mortality and prolonged hospital stays there are compelling clinical and financial reasons to improve the identification and treatment of delirium Dexmedetomidine a selective alpha2-adrenergic receptor agonist may be an alternative to current postoperative sedation when it comes to lowering the incidence of delirium
Comparisons The use of postoperative at sternal closure dexmedetomidine will be compared to current standards of care propofol and midazolam for postoperative sedation
Comparisons The use of postoperative at sternal closure dexmedetomidine will be compared to current standards of care propofol and midazolam for postoperative sedation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None