Ignite Creation Date:
2024-05-06 @ 3:33 PM
Last Modification Date:
2024-10-26 @ 1:52 PM
Study NCT ID:
NCT04672382
Status:
COMPLETED
Last Update Posted:
2023-01-18
First Post:
2020-12-14
Brief Title:
Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine
Sponsor:
Aalborg University
Organization:
Aalborg University
Study Overview
Official Title:
Effect of Intradermal Morphine Application on Histaminergic and Non-histaminergic Itch and Related TRPV1 and Antihistamine Treatment
Status:
COMPLETED
Status Verified Date:
2023-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to the effect of opioid morphine intradermal application on histaminergic and non-histaminergic itch In particular we would like to demonstrate that also peripheral administration of morphine may affect mast cell release of histamine
Detailed Description:
Opioids ie substances extracted from opium poppies eg morphine are used for treatment of both acute and chronic pain conditions as well as in surgical procedures Opioids render effective pain relief however they may cause bothersome itch as a side effect With this series of experiments we wish to clarify how an injection with morphine in the skin layer called dermis located right below the upper skin will affect itch
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None