Ignite Creation Date:
2024-05-05 @ 5:17 PM
Last Modification Date:
2024-10-26 @ 9:30 AM
Study NCT ID:
NCT00425009
Status:
COMPLETED
Last Update Posted:
2007-01-22
First Post:
2007-01-18
Brief Title:
Therapeutic Effects of Berberine in Patients With Type 2 Diabetes
Sponsor:
Shanghai Jiao Tong University School of Medicine
Organization:
Shanghai Jiao Tong University School of Medicine
Study Overview
Official Title:
Effects of Berberine on Improvement of Glucose and Lipid Metabolism in Patients With Type 2 Diabetes
Status:
COMPLETED
Status Verified Date:
2007-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether berberine is effective in the treatment of type 2 diabetes
Detailed Description:
Type 2 diabetes is health threats worldwide However treatment of this disease is limited by availability of effective medicines All of the existing oral hypoglycemic agents have secondary failure after long term administration Thus new oral medicines are needed for long term control of blood glucose in patients with type 2 diabetes In diabetes care dietary approaches have drawn more and more attention in the prevention and treatment of hyperglycemia Generally regarded as safe GRAS plants have been widely used for their benefits in antioxidation anti-inflammation anticancer anti-obesity and anti-diabetes Numerous botanical products such as pigments that include anthocyanins and flavonoids have been consumed or studied for anti-obesity and anti-diabetes However most of these botanical products are mixtures of multiple compounds It is difficult to control their quality in the study or production Up to now as a single purified compound berberine is demonstrated to have hypoglycemic effect in vitro and in vivo Berberine is the main active component of Coptis chinensis French which was used for thousands of years in China in the treatment of human diseases including diabetes
Comparisons Effects of berberine compared with metformin in newly diagnosed type 2 diabetic patients
Comparisons Effects of berberine compared with metformin in newly diagnosed type 2 diabetic patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None