Ignite Creation Date:
2024-05-06 @ 3:39 PM
Last Modification Date:
2024-10-26 @ 1:53 PM
Study NCT ID:
NCT04700007
Status:
COMPLETED
Last Update Posted:
2022-01-27
First Post:
2021-01-06
Brief Title:
Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine Second Sub-Project
Sponsor:
Aalborg University
Organization:
Aalborg University
Study Overview
Official Title:
Effect of Intradermal Morphine Application on Histaminergic and Non-histaminergic Itch and Related TRPV1 and Antihistamine Treatments 2nd Sub-project
Status:
COMPLETED
Status Verified Date:
2022-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of our 2nd sub-project is to clarify if the capsaicin receptor TRPV1 is implicated in the mechanism of morphine-induced mast cell degranulation Moreover we also aim to clarify if the mechanism of opioid-induced itch relay on the histaminergic pathway by using the antihistamine diphenhydramine to suppress the release of histamine from peripheral mast cells
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None