Ignite Creation Date:
2024-05-05 @ 5:19 PM
Last Modification Date:
2024-10-26 @ 9:30 AM
Study NCT ID:
NCT00436475
Status:
COMPLETED
Last Update Posted:
2019-07-30
First Post:
2007-02-16
Brief Title:
Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes
Sponsor:
Tufts Medical Center
Organization:
Tufts Medical Center
Study Overview
Official Title:
Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes
Status:
COMPLETED
Status Verified Date:
2019-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CaDDM
Brief Summary:
The purpose of the randomized trial is to quantify the effect of vitamin D and calcium supplementation on beta-cell function insulin sensitivity glucose tolerance and systemic inflammation and other cardiometabolic outcomes in ambulatory adults at high risk for type 2 diabetes
Detailed Description:
There is animal and human observational evidence to suggest that vitamin D and calcium are important in modifying t2DM risk but there are critical gaps in our knowledge about the clinical magnitude of the association with t2DM and potential mechanisms in humans We are conducting a randomized trial to quantify the effect of vitamin D and calcium supplementation on beta-cell function insulin sensitivity glucose tolerance and systemic inflammation and other cardiometabolic outcomes in ambulatory adults at high risk for t2DM We anticipate that the research proposed in this application is significant because it will provide the basis for defining feasible nutritional interventions that promotes prevention of t2DM Based on the results of the proposed studies and future work in this area vitamin D and calcium supplementation can assume an important role in the treatment of t2DM and in the prevention of the disease in the 41 million Americans who are at risk of developing t2DM
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01DK076092 | NIH | None | None |
| DK76092 | US NIH GrantContract | None | httpsreporternihgovquickSearchR01DK076092 |