Ignite Creation Date:
2024-05-05 @ 5:19 PM
Last Modification Date:
2024-10-26 @ 9:30 AM
Study NCT ID:
NCT00433797
Status:
COMPLETED
Last Update Posted:
2013-12-19
First Post:
2007-02-09
Brief Title:
Dietary Intervention With Phytochemicals and Polyunsaturated Fatty Acids in Prostate Cancer Patients
Sponsor:
University of Oslo
Organization:
University of Oslo
Study Overview
Official Title:
Prostate Phytochemical PUFA Intervention - a Phase III Study
Status:
COMPLETED
Status Verified Date:
2013-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
We will study the effect of dietary intervention in patients with prostate cancer Outcomes include serum PSA kinetics as well as biomarkers of inflammation antioxidant status oxidative stress and oxidative damage in blood cells plasma urine and prostate tissues
Detailed Description:
A total of 102 patients with localized prostate cancer will be included in the study A the time of inclusion the participants will be randomized to three groups
The intervention groups includes control group tomato group and multi-diet group The intervention period is three week and will be completed before prostatectomy or radiation therapy
Biomarkers og inflammation includes acute phase proteins cytokines chemokines and other inflammatory mediators Biomarker of antioxidant status includes vitamin C vitamin E glutathione carotenoids total antioxidant capacity and total phenolics Oxidative stress markers includes malondialdehyde isoprostanes 8-hydroxy-deoxyguanosine oxidized vitamin C total lipidperoxides d-ROM and protein carbonyls
The intervention groups includes control group tomato group and multi-diet group The intervention period is three week and will be completed before prostatectomy or radiation therapy
Biomarkers og inflammation includes acute phase proteins cytokines chemokines and other inflammatory mediators Biomarker of antioxidant status includes vitamin C vitamin E glutathione carotenoids total antioxidant capacity and total phenolics Oxidative stress markers includes malondialdehyde isoprostanes 8-hydroxy-deoxyguanosine oxidized vitamin C total lipidperoxides d-ROM and protein carbonyls
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| S-06187 REK Sør | OTHER | None | None |
| 2006-18 RRHF | OTHER | Oslo University Hospital | None |