Ignite Creation Date:
2024-05-05 @ 5:20 PM
Last Modification Date:
2024-10-26 @ 9:30 AM
Study NCT ID:
NCT00431301
Status:
COMPLETED
Last Update Posted:
2017-04-10
First Post:
2007-02-01
Brief Title:
Risk Factors for Progressive Supranuclear Palsy PSP
Sponsor:
University of Louisville
Organization:
University of Louisville
Study Overview
Official Title:
Genetic and Environmental Risk Factors for PSP
Status:
COMPLETED
Status Verified Date:
2017-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Progressive supranuclear palsy PSP is the most common atypical parkinsonian movement disorder This study will determine the role of specific genetic occupational and environmental components in the development of PSP by evaluating patients with this disorder and age and gender matched controls
Detailed Description:
This proposal will determine 1 if there is an association between PSP and specific genes of interest 2 if there is an association between PSP and occupational andor environmental chemical exposures functionally or structurally similar to known parkinsonian toxicants and 3 if hypertension or traumatic brain injury prior to symptom-onset is associated with PSP To disentangle the complex etiology of PSP this case-control multicenter study involves 500 PSP cases 500 agegender matched primary controls and 500 secondary controls for genetic confirmation Understanding the etiology of PSP may also help explain the causes of other related diseases such as Alzheimers disease This multidisciplinary team of movement disorder specialists epidemiologists geneticists biostatisticians industrial hygienist and toxicologist is well suited to unravel the etiology of PSP
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1R01AG024040-01A2 | NIH | None | httpsreporternihgovquickSearch1R01AG024040-01A2 |