Ignite Creation Date:
2024-05-05 @ 5:21 PM
Last Modification Date:
2024-10-26 @ 9:30 AM
Study NCT ID:
NCT00433264
Status:
COMPLETED
Last Update Posted:
2009-03-05
First Post:
2007-02-07
Brief Title:
The Interrelation of the Vasculature Endothelium Bone Metabolism and Uremic Toxins in Peritoneal Dialysis
Sponsor:
Universitaire Ziekenhuizen KU Leuven
Organization:
Universitaire Ziekenhuizen KU Leuven
Study Overview
Official Title:
The Interrelation of the Vasculature Endothelium Bone Metabolism and Uremic Toxins in Peritoneal Dialysis
Status:
COMPLETED
Status Verified Date:
2009-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
INVEST-PD
Brief Summary:
Despite major advances in the treatment of chronic kidney disease the age and sex matched mortality far exceeds that of the normal population As in the normal population the majority of deaths are related to cardiovascular disease Mounting data point to the lethal synergy between chronic kidney disease and cardiovascular disease This relation is present from early stages of chronic kidney disease on
Several uremic toxins have been demonstrated to play an important role in kidney disease related endothelial dysfunction In peritoneal dialysis patients data on the relation between uremic toxins endothelial dysfunction and microparticles are lacking
The investigators hypothesize that endothelial dysfunction and uremic toxins are interrelated in peritoneal dialysis patients
Several uremic toxins have been demonstrated to play an important role in kidney disease related endothelial dysfunction In peritoneal dialysis patients data on the relation between uremic toxins endothelial dysfunction and microparticles are lacking
The investigators hypothesize that endothelial dysfunction and uremic toxins are interrelated in peritoneal dialysis patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None