Ignite Creation Date:
2024-05-05 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00005206
Status:
COMPLETED
Last Update Posted:
2016-02-18
First Post:
2000-05-25
Brief Title:
Calcium Intake Metabolism and Gestational Blood Pressure
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2002-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To determine if low dietary calcium intake and disturbances in maternal calcium metabolism were associated with increases in blood pressure in late pregnancy
Detailed Description:
BACKGROUND
The importance of maintaining dietary calcium intake and normal calcium metabolism for optimal regulation of arterial blood pressure has been demonstrated in humans and animals Recent reports have suggested that low dietary calcium intake and disturbances in maternal calcium metabolism are associated with increases in blood pressure in late gestation These factors may be associated with an increased risk of developing pregnancy-induced hypertension
This study was conducted in response to a Request for Applications on Research on Hypertension in Pregnancy jointly released in 1986 by the National Heart Lung and Blood Institute and the National Institute of Child Health and Human Development
DESIGN NARRATIVE
Blood pressure nutrient intake and markers of calcium metabolism were prospectively assessed in normal pregnant women Nutrient intakes including dietary calcium were assessed during gestation weeks 24 28 32 36 and the postpartum period using 3-day food records and 24-hour dietary recalls Concomitantly serum measures of calcium metabolism were assessed including serum total and ionized calcium parathyroid hormone calcitonin vitamin D concentration serum magnesium phosphorus sodium and potassium concentrations During weeks 24 and 32 urinary excretion of sodium calcium magnesium potassium phosphorus cAMP and creatinine were measured Blood pressures were measured at every prenatal visit and postpartum Measures of infant growth and blood pressure were assessed at 1 6 and 12 months of age to determine if maternal dietary calcium intake exerted long-term influences on infant development and blood pressure
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
The importance of maintaining dietary calcium intake and normal calcium metabolism for optimal regulation of arterial blood pressure has been demonstrated in humans and animals Recent reports have suggested that low dietary calcium intake and disturbances in maternal calcium metabolism are associated with increases in blood pressure in late gestation These factors may be associated with an increased risk of developing pregnancy-induced hypertension
This study was conducted in response to a Request for Applications on Research on Hypertension in Pregnancy jointly released in 1986 by the National Heart Lung and Blood Institute and the National Institute of Child Health and Human Development
DESIGN NARRATIVE
Blood pressure nutrient intake and markers of calcium metabolism were prospectively assessed in normal pregnant women Nutrient intakes including dietary calcium were assessed during gestation weeks 24 28 32 36 and the postpartum period using 3-day food records and 24-hour dietary recalls Concomitantly serum measures of calcium metabolism were assessed including serum total and ionized calcium parathyroid hormone calcitonin vitamin D concentration serum magnesium phosphorus sodium and potassium concentrations During weeks 24 and 32 urinary excretion of sodium calcium magnesium potassium phosphorus cAMP and creatinine were measured Blood pressures were measured at every prenatal visit and postpartum Measures of infant growth and blood pressure were assessed at 1 6 and 12 months of age to determine if maternal dietary calcium intake exerted long-term influences on infant development and blood pressure
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL040005 | NIH | None | httpsreporternihgovquickSearchR01HL040005 |