Ignite Creation Date:
2024-05-06 @ 4:13 PM
Last Modification Date:
2024-10-26 @ 2:06 PM
Study NCT ID:
NCT04917003
Status:
UNKNOWN
Last Update Posted:
2021-06-29
First Post:
2021-06-01
Brief Title:
Safety and Efficacy of Remote Ischemic Conditioning Combined EDAS on Ischemic Moyamoya Disease
Sponsor:
Capital Medical University
Organization:
Capital Medical University
Study Overview
Official Title:
Safety and Efficacy of Remote Ischemic Conditioning Combined EncephaloduroarteriosynangiosisEDASon Ischemic Moyamoya Disease A Prospective Randomized Controlled Study
Status:
UNKNOWN
Status Verified Date:
2021-06
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
RIC-IMD
Brief Summary:
Encephaloduroarteriosynangiosis EDAS is widely used as an indirect technique for treatment of moyamoya disease Nevertheless this indirect surgery tends to establish insufficient collateral circulation in most adult MMD patients Nowadays there is a lack of adjuvant therapies for improving collateral circulation induced by indirect revascularization This study aims to explore whether remote ischemic conditioning can improve the collateral circulation after indirect revascularization
Detailed Description:
Encephaloduroarteriosynangiosis EDAS is widely used as an indirect technique for treatment of moyamoya disease Nevertheless this indirect surgery tends to establish insufficient collateral circulation in most adult MMD patients Nowadays there is a lack of adjuvant therapies for improving collateral circulation induced by indirect revascularization Remote ischemic conditioning RIC is a noninvasive approach protecting the brain by inflating and deflating blood-pressure cuff placed on the upper limbs It has been confirmed to improve cerebral perfusion by promoting angiogenesis and arteriogenesis in ischemic animal brain In addition daily remote ischemic conditioning is a promising technique to ameliorate chronic cerebrovascular disease like intracranial atherosclerotic stenosis small-vessel disease
Thus this study aims to explore whether remote ischemic conditioning can improve the collateral circulation after indirect revascularization
Thus this study aims to explore whether remote ischemic conditioning can improve the collateral circulation after indirect revascularization
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None