Ignite Creation Date:
2024-05-06 @ 4:14 PM
Last Modification Date:
2024-10-26 @ 2:06 PM
Study NCT ID:
NCT04924335
Status:
COMPLETED
Last Update Posted:
2021-08-20
First Post:
2021-05-22
Brief Title:
The Effects of Erector Spinae Plane ESP Block on Surgery-related Stress Response in Cardiac Surgery With ERAS
Sponsor:
Ankara City Hospital Bilkent
Organization:
Ankara City Hospital Bilkent
Study Overview
Official Title:
Ultrasound-guided Erector Spinae Plane ESP Block Attenuates Surgery-related Stress Response in Cardiac Surgery Patients Undergoing Enhanced Recovery After Surgery ERAS Program
Status:
COMPLETED
Status Verified Date:
2021-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Surgery-induced pain reveals its own metabolic and inflammatory responses resulting in a further increase in noxious pathways that are already occurring Even though it is difficult to distinguish whether the metabolic and inflammatory responses are pain-induced or surgical-induced it is clear that pain can cause a response This study aims to investigate the effects of erector spinae plane block on surgery-related stress response with enhanced recovery after cardiac surgery protocol
Detailed Description:
The Enhanced Recovery After Cardiac Surgery ERAS Cardiac program includes a perioperative multimodal opioid-sparing pain management plan as an essential component of any comprehensive program A multimodal pain management plan is nonopioid systemic analgesic agents regional and local anesthetic techniques and judicious use of opioids This study aims to examine inflammatory and hematological parameters in patients who underwent cardiac surgery with ERAS with and without preoperative bilateral erector spinae plane block ESP For this purpose the presence of an obstacle ESP block application in the preoperative period will be investigated in patients who are prepared for cardiac surgery according to ERAS principles and the patients group will be determined accordingly An analgesia protocol that does not include a regional technique will be applied to the patient in cases such as the patients refusal to allow preoperative block and the presence of a situation that does not allow blockage in the block area The perioperative characteristics of ERAS patients with and without ESP block will be examined intraoperative lactate and preop-postoperative hemogram-albumin-C reactive protein parameters will be recorded
ERAS patients with ESP block After preparation in accordance with the ERAS protocol ultrasound-guided bilateral ESP block will be performed with 20 ml of 0025 bupivacaine at T5-7 levels in patients taken to the operating room in the preoperative period and will be administered intraoperative low-dose remifentanil infusion and sevoflurane anesthesia
ERAS patients without ESP block After preparation according to the ERAS protocol patients will be administered lidocaine ketamine paracetamol and intraoperative low-dose remifentanil infusion and sevoflurane anesthesia
ERAS patients with ESP block After preparation in accordance with the ERAS protocol ultrasound-guided bilateral ESP block will be performed with 20 ml of 0025 bupivacaine at T5-7 levels in patients taken to the operating room in the preoperative period and will be administered intraoperative low-dose remifentanil infusion and sevoflurane anesthesia
ERAS patients without ESP block After preparation according to the ERAS protocol patients will be administered lidocaine ketamine paracetamol and intraoperative low-dose remifentanil infusion and sevoflurane anesthesia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None