Ignite Creation Date:
2024-05-05 @ 5:25 PM
Last Modification Date:
2024-10-26 @ 9:31 AM
Study NCT ID:
NCT00455377
Status:
COMPLETED
Last Update Posted:
2013-06-13
First Post:
2007-03-30
Brief Title:
Lung Function and Airway Inflammation in Portland Cement Workers
Sponsor:
Sykehuset Telemark
Organization:
Sykehuset Telemark
Study Overview
Official Title:
Airway Inflammation in Cement Dust Exposed Workers
Status:
COMPLETED
Status Verified Date:
2013-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SPUTUM
Brief Summary:
The aim of the study is to examine inflammation in the airways and in peripheral blood in workers in a cement plant i Norway
Detailed Description:
OBJECTIVE Former studies have presented conflicting data on the association between exposure to Portland cement dust and respiratory effects Our goal is to examine inflammation in the airways and in peripheral blood in subjects exposed to cement-dust
METHODS All non smoking dust exposed workers from one department in the largest cement plant in Norway are invited to participate The workers will perform spirometry and induced sputum IS after a period of regular work with cement dust exposure and again after a minimum of 5 days without exposure Information on respiratory symptoms allergy and former respiratory disease will be given on a self-reported questionnaire IS was performed and processed as described by Pin et al Differential cell counts will be carried out Inflammatory markers in induced sputum and in peripheral blood will be measured We want to use a crossover design were the cases are used as their own controls but we will also include external controls
METHODS All non smoking dust exposed workers from one department in the largest cement plant in Norway are invited to participate The workers will perform spirometry and induced sputum IS after a period of regular work with cement dust exposure and again after a minimum of 5 days without exposure Information on respiratory symptoms allergy and former respiratory disease will be given on a self-reported questionnaire IS was performed and processed as described by Pin et al Differential cell counts will be carried out Inflammatory markers in induced sputum and in peripheral blood will be measured We want to use a crossover design were the cases are used as their own controls but we will also include external controls
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None