Ignite Creation Date:
2024-05-05 @ 5:25 PM
Last Modification Date:
2024-10-26 @ 9:32 AM
Study NCT ID:
NCT00456469
Status:
UNKNOWN
Last Update Posted:
2007-04-05
First Post:
2007-04-04
Brief Title:
Diagnosis of Active and Latent TB Infection With IFN-y Assays in African Children
Sponsor:
Liverpool School of Tropical Medicine
Organization:
Liverpool School of Tropical Medicine
Study Overview
Official Title:
Diagnosis of Active and Latent TB Infection With IFN-y Assays in African Children
Status:
UNKNOWN
Status Verified Date:
2007-04
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ALTAC
Brief Summary:
Study based in Southern Ethiopia Purpose - to explore if children in contact with adults with TB have positive acute reactants such as IFN-y and other cytokine responses if these responses discriminate between high and low risk of disease progression and whether these could be incorporated into improved diagnostic approaches
Detailed Description:
The study follows children in contact with TB Those with positive TST will be offered chemoprophylaxis and all children will be followed for 2 years to describe IFN-y responses over time identify symptoms of active TB and if these symptoms are associated with IFN-y and other cytokine responses
Children with suspicion of TB attending health centres will also be investigated using routine diagnostic tests and IFN-y and other cytokines responses to evaluate if the latter could be used in improved diagnostic approaches
Children with suspicion of TB attending health centres will also be investigated using routine diagnostic tests and IFN-y and other cytokines responses to evaluate if the latter could be used in improved diagnostic approaches
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None