Ignite Creation Date:
2024-05-05 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001414
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Mapping Personality Traits to Genes
Sponsor:
National Institute of Mental Health NIMH
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Mapping Personality Traits to Genes
Status:
COMPLETED
Status Verified Date:
2002-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Previous research involving families twins and adoption all support the idea that there is a substantial heritable aspect to personality
The goal of this research study is to determine how genetics influence heritable personality traits The work will focus on how genetics affect the chemical messengers which brain cells use to communicate with each other neurotransmitters
The study involves collecting personality data and DNA samples from related individuals primarily male siblings and female siblings but also including parents Genetic tests performed on these samples will continue to focus on variations in genes which potentially effect brain neurotransmission
This research has the potential to advance knowledge of genetic influences on human behavior that may be relevant both to normal personality and to psychopathology
The goal of this research study is to determine how genetics influence heritable personality traits The work will focus on how genetics affect the chemical messengers which brain cells use to communicate with each other neurotransmitters
The study involves collecting personality data and DNA samples from related individuals primarily male siblings and female siblings but also including parents Genetic tests performed on these samples will continue to focus on variations in genes which potentially effect brain neurotransmission
This research has the potential to advance knowledge of genetic influences on human behavior that may be relevant both to normal personality and to psychopathology
Detailed Description:
Building on family twin and adoption studies suggesting that substantial aspects of personality are heritable research under this protocol explores potential genetic influences on normal personality dimensions We have previously reported associations between variation in neurotransmitter system genes and variation in personality traits both across and within families in a sample of the general population This study involves collecting personality data and DNA samples from related individuals primarily male siblings and female siblings but also including parents Genetic tests performed on these samples will continue to focus on variations in genes which potentially affect brain neurotransmission In some cases participants are recontacted to specifically investigate whether identified variations in neurotransmitter system genes actually affect neurotransmission Large population samples are needed in this research particularly since a new epidemiologically standard population sample will be obtained This research has the potential to advance knowledge of genetic influences on human behavior that may be relevant both to normal personality and to psychopathology
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 94-M-0122 | None | None | None |