Ignite Creation Date:
2024-05-05 @ 5:29 PM
Last Modification Date:
2024-10-26 @ 9:32 AM
Study NCT ID:
NCT00461227
Status:
COMPLETED
Last Update Posted:
2012-12-19
First Post:
2007-04-13
Brief Title:
Effect of Heredity and Environment on Asthma Development and Severity in Puerto Rican Children
Sponsor:
University of Pittsburgh
Organization:
University of Pittsburgh
Study Overview
Official Title:
Genes Home Allergens and Asthma in Puerto Rican Children
Status:
COMPLETED
Status Verified Date:
2012-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Asthma is a major public health problem among Puerto Ricans Little is known however about the effect of heredity and environment on the development and severity of asthma in this population This study will examine the relationship between asthma and certain genetic and environmental factors in Puerto Rican children
Detailed Description:
Asthma is a chronic disease that causes constriction of the airways People with asthma may experience wheezing coughing chest tightness and trouble breathing Although asthma is a major public health problem among Puerto Ricans little research has been done to determine the influence of heredity and environment on the disease in this population To learn more about these relationships this study will examine the effects of certain genes and allergens on the development and severity of asthma in Puerto Rican children
This observational study will recruit both children with asthma and children without asthma Participants will meet with study staff twice during the study The first visit will take place at participants homes Participants will complete questionnaires about demographics respiratory and general health and household characteristics Lung function testing collection of blood samples and collection of household dust samples will also take place at the home-based visit The second visit will take place at the study site At this visit participants will undergo allergy tests on the skin and a methacholine challenge test to assess their airway responsiveness and asthma severity The methacholine challenge test will involve inhaling mist through a mouthpiece and blowing forcefully into a special apparatus called a spirometer Parents will be asked to provide information about their childrens exposure to pets in early life Each visit will last approximately 15 hours and will be scheduled close to the date on which a participant enters the study
This observational study will recruit both children with asthma and children without asthma Participants will meet with study staff twice during the study The first visit will take place at participants homes Participants will complete questionnaires about demographics respiratory and general health and household characteristics Lung function testing collection of blood samples and collection of household dust samples will also take place at the home-based visit The second visit will take place at the study site At this visit participants will undergo allergy tests on the skin and a methacholine challenge test to assess their airway responsiveness and asthma severity The methacholine challenge test will involve inhaling mist through a mouthpiece and blowing forcefully into a special apparatus called a spirometer Parents will be asked to provide information about their childrens exposure to pets in early life Each visit will last approximately 15 hours and will be scheduled close to the date on which a participant enters the study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL079966-01A2 | NIH | None | httpsreporternihgovquickSearchR01HL079966-01A2 |