Ignite Creation Date:
2024-05-06 @ 5:00 PM
Last Modification Date:
2024-10-26 @ 2:20 PM
Study NCT ID:
NCT05162430
Status:
COMPLETED
Last Update Posted:
2021-12-17
First Post:
2021-12-04
Brief Title:
Inhibitory Effect of Propofol on Perineal Pruritus in Patients Undergoing Day Surgery
Sponsor:
Yangzhou University
Organization:
Yangzhou University
Study Overview
Official Title:
Inhibitory Effect of Different Doses of Propofol on Perineal Pruritus Caused by Dexamethasone Sodium Phosphate in Patients Undergoing Day Surgery
Status:
COMPLETED
Status Verified Date:
2021-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
OBJECTIVE To investigate the inhibitory effect of different doses of propofol on perineal pruritus induced by dexamethasone sodium phosphate injection in women with a view to providing clinical reference for comfortable clinical care in day surgery
METHODS One hundred and fifty patients with ASA classification I or II undergoing elective day surgery were randomly divided into six groups of P1 P2 P3 P4 P5 and D1 with 25 cases in each group Before administration of dexamethasone propofol injection 01 mgkg 02 mgkg 03 mgkg 04 mgkg and 05 mgkg were given intravenously in groups P1 P2 P3 P4 and P5 respectively injection rate was 5 s followed by 30 s of intravenous dexamethasone sodium phosphate 10 mg in all five groups 5 ml of saline was given in group D1 and 30 s After that dexamethasone sodium phosphate injection was given injection speed was 5s in all five groups The perineal itching the onset and duration of itching the visual analogue score VAS of itching the sleep disorder sedation score Ramsay score and the occurrence of adverse reactions were recorded in the five groups
METHODS One hundred and fifty patients with ASA classification I or II undergoing elective day surgery were randomly divided into six groups of P1 P2 P3 P4 P5 and D1 with 25 cases in each group Before administration of dexamethasone propofol injection 01 mgkg 02 mgkg 03 mgkg 04 mgkg and 05 mgkg were given intravenously in groups P1 P2 P3 P4 and P5 respectively injection rate was 5 s followed by 30 s of intravenous dexamethasone sodium phosphate 10 mg in all five groups 5 ml of saline was given in group D1 and 30 s After that dexamethasone sodium phosphate injection was given injection speed was 5s in all five groups The perineal itching the onset and duration of itching the visual analogue score VAS of itching the sleep disorder sedation score Ramsay score and the occurrence of adverse reactions were recorded in the five groups
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None