Ignite Creation Date:
2024-05-05 @ 5:31 PM
Last Modification Date:
2024-10-26 @ 9:33 AM
Study NCT ID:
NCT00474344
Status:
COMPLETED
Last Update Posted:
2022-05-18
First Post:
2007-05-14
Brief Title:
Genetic Linkage Study of Idiopathic Talipes Equinovarus ITEV Clubfoot
Sponsor:
University of British Columbia
Organization:
University of British Columbia
Study Overview
Official Title:
Genetic Linkage Study of Idiopathic Talipes Equinovarus ITEV Clubfoot
Status:
COMPLETED
Status Verified Date:
2017-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this study is to identify and characterize the genetic loci causing idiopathic talipes equinovarus clubfoot
The hypothesis is that a few genes account for a substantial fraction of ITEV and that these genes can be identified in defined populations Towards this goal in preliminary studies Dr Hechts group has identified two genes NAT2 and CASP10 which demonstrate evidence for linkage and association to ITEV
The hypothesis is that a few genes account for a substantial fraction of ITEV and that these genes can be identified in defined populations Towards this goal in preliminary studies Dr Hechts group has identified two genes NAT2 and CASP10 which demonstrate evidence for linkage and association to ITEV
Detailed Description:
Blood Collection For this study the investigators need to obtain blood samples from members of families in which clubfoot has occurred more specifically blood samples from the affected child and both parents DNA will be extracted from blood samples The DNA will then be tested to look for genetic factors that cause clubfoot
Study Questionnaires As well as the blood samples the investigators have a short questionnaire for the mother of the child with clubfoot to complete
Study Questionnaires As well as the blood samples the investigators have a short questionnaire for the mother of the child with clubfoot to complete
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None