Ignite Creation Date:
2024-05-05 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001208
Status:
RECRUITING
Last Update Posted:
2024-07-15
First Post:
1999-11-03
Brief Title:
Botulinum Toxin for the Treatment of Involuntary Movement Disorders
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Botulinum Toxin for the Treatment of Neurological Disorders
Status:
RECRUITING
Status Verified Date:
2024-08-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Botulism is a severe form of food poisoning caused by bacteria This bacteria produces several toxins one of which is botulinum toxin A This toxin causes the symptoms of food poisoning Small amounts of botulinum toxin A have been used to treat speech disorders such as stuttering and problems with the muscles of the eyes
The study examines the effectiveness of botulinum toxin as treatment for a variety of movement disorders The goals of the study are to refine the technique of treatment to provide the best results to improve the understanding of how botulinum toxin works on movement disorders and find other conditions that may be treatable with botulinum toxin
In addition researchers also plan to study the possible use of botulinum toxin F alone and in combination with botulinum toxin A in patients who do not respond to botulinum A toxin treatmentTAB
The study examines the effectiveness of botulinum toxin as treatment for a variety of movement disorders The goals of the study are to refine the technique of treatment to provide the best results to improve the understanding of how botulinum toxin works on movement disorders and find other conditions that may be treatable with botulinum toxin
In addition researchers also plan to study the possible use of botulinum toxin F alone and in combination with botulinum toxin A in patients who do not respond to botulinum A toxin treatmentTAB
Detailed Description:
The efficacy of botulinum toxin BTX has now been demonstrated for a variety of diseases associated with involuntary muscles spasms or movement The application of botulinum toxin therapy to movement disorders requires treatment tailored to the individual patient and specific techniques of injection This protocol 1 allows us to follow the natural history of subjects with movement disorders who receive standard botox injections for treatment of movement disorders and 2 allows us to provide botulinum toxin injections for patients participating in other studies on the physiology of sensorimotor systems and on the physiological effects of botulinum toxin
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 85-N-0195 | None | None | None |