Ignite Creation Date:
2024-05-05 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001232
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders
Sponsor:
National Institute of Mental Health NIMH
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Pituitary Gonadotropin Response to GnRH Stimulation in Menstrual Climacteric and Menopause-Related Mood and Behavioral Disorders
Status:
COMPLETED
Status Verified Date:
1999-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The normal menstrual cycle is produced by a series of hormonal signals that starts with the release of gonadotropin-releasing hormone GnRH from the hypothalamus The hypothalamus is located in the brain and is often referred to as the master gland GnRH then acts on the pituitary gland and causes it to release two hormones follicle stimulating hormone FSH and lutenizng hormone LH LH and FSH act on the ovary and cause it to release the hormones directly involved in menstruation estrogen and progesterone
The purpose of this research study is to evaluate the hypothalamic-pituitary-gonadal axis activity as measured by pituitary hormones FSH and LH in response to intravenous doses of gonadotropin releasing hormone GnRH in menstrual cycle-related hormones
The purpose of this research study is to evaluate the hypothalamic-pituitary-gonadal axis activity as measured by pituitary hormones FSH and LH in response to intravenous doses of gonadotropin releasing hormone GnRH in menstrual cycle-related hormones
Detailed Description:
This protocol is designed to accompany clinical protocol 81-M-0126 The Phenomenology and Biophysiology of Menstrually Regulated Mood and Behavior Disorders as well as the submitted protocol The Phenomenology and Biophysiology of Climacteric and Menopause-Related Mood and Behavioral Disorders Its purpose will be to evaluate hypothalamic-pituitary-gonadal axis regulation as measured by pituitary gonadotropin ie follicle stimulating hormone FSH and luteinizing hormone LH response to intravenous administration of gonadotropin releasing hormone GnRH in menstrual cycle-related mood disorders
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 88-M-0132 | None | None | None |