Ignite Creation Date:
2024-05-06 @ 5:59 PM
Last Modification Date:
2024-10-26 @ 2:39 PM
Study NCT ID:
NCT05503706
Status:
UNKNOWN
Last Update Posted:
2022-08-17
First Post:
2022-08-12
Brief Title:
Effects on the Scalp Lipids and TEWL of a 1 Selenium Disulfide and 1 Salicylic Acid Antidandruff Shampoo on Dandruff Scalp
Sponsor:
LOreal
Organization:
LOreal
Study Overview
Official Title:
Evaluation of the Antidandruff Effect of a Shampoo on Subjects With Dandruff and Slight Itching Single-blind Monocentric Study Realized Under Dermatological Control
Status:
UNKNOWN
Status Verified Date:
2022-08
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study was to investigate the changes in the scalp lipids and TEWL in dandruff subjects treated by 1 Selenium Disulfide SeS21 salicylic acid-based shampoo after an antidandruff treatment and after a remanence phase
Detailed Description:
Dandruf often has a substantial negative impact on quality of life The proliferation of Malassezia specie has been shown to be linked to dandruff Yet the sebum is essential for the growth of Malassezia restricta
The sebum is mainly constituted by waxes squalene and triglycerides The triglycerides are partially transformed in free fatty acids while the squalene can be oxidized Therefore the change in lipids can be of interest for dandruff studies
The scalp barrier function of a dandruff scalp is known to be altered and must recover after an antidandruff treatment
The aim of this study is to investigate the change of the scalp lipids and TEWL after a 1 selenium disulfide and 1 salicylic acid antidandruff shampoo on dandruff scalp and after a remanence period
The sebum is mainly constituted by waxes squalene and triglycerides The triglycerides are partially transformed in free fatty acids while the squalene can be oxidized Therefore the change in lipids can be of interest for dandruff studies
The scalp barrier function of a dandruff scalp is known to be altered and must recover after an antidandruff treatment
The aim of this study is to investigate the change of the scalp lipids and TEWL after a 1 selenium disulfide and 1 salicylic acid antidandruff shampoo on dandruff scalp and after a remanence period
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None