Ignite Creation Date:
2024-05-05 @ 6:34 PM
Last Modification Date:
2024-10-26 @ 9:34 AM
Study NCT ID:
NCT00502554
Status:
TERMINATED
Last Update Posted:
2011-07-26
First Post:
2007-07-16
Brief Title:
Extracorporeal Photopheresis in Patients With Bronchiolitis Obliterans Syndrome BOS After Lung Transplantation
Sponsor:
Hannover Medical School
Organization:
Hannover Medical School
Study Overview
Official Title:
Extracorporeal Photopheresis in Patients With Bronchiolitis Obliterans Syndrome BOS After Lung Transplantation
Status:
TERMINATED
Status Verified Date:
2008-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
insufficient patient recruitment and ECP capacity
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Investigation of photopheresis as new therapy regimen in patients with bronchiolitis obliterans syndrome after lung transplantation in a controlled randomized study
Detailed Description:
Bronchiolitis obliterans syndrome is the major cause of mortality after lung transplantation 5 years after lung transplantation about 50 of all patients have this syndrome There are nearly none therapy options Besides effective therapy of any gastrooesophageal reflux and an oral medication with azithromycin none further regimens are known Photopheresis could show in several studies a benefit for patients with gvhd after bone marrow transplantation or for chronic rejection after any other solid organ transplantation Just little case reports could show beneficial effect in patients with bos after lung transplantation
This is the first controlled randomized study with patients with bos after lung transplantation to investigate the effectiveness of this therapy in that patients
This is the first controlled randomized study with patients with bos after lung transplantation to investigate the effectiveness of this therapy in that patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None