Ignite Creation Date:
2024-05-06 @ 6:09 PM
Last Modification Date:
2024-10-26 @ 2:43 PM
Study NCT ID:
NCT05568433
Status:
COMPLETED
Last Update Posted:
2022-10-05
First Post:
2022-09-25
Brief Title:
New Biomarkers in the Intracystic Liquid of Inflammatory and Non-inflammatory Pancreatic Cysts
Sponsor:
Iuliu Hatieganu University of Medicine and Pharmacy
Organization:
Iuliu Hatieganu University of Medicine and Pharmacy
Study Overview
Official Title:
New Biomarkers in the Intracystic Liquid of Cystic Pancreatic Lesions
Status:
COMPLETED
Status Verified Date:
2022-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Due to the advances made in the field of the imaging techniques and their common use pancreatic cysts are more and more incidentally found
Pancreatic pseudocysts can be misdiagnosed as cystic neoplasms in particular when there is no clinical history of acute or chronic pancreatitis Pancreatic cystic neoplasms on the other hand are rare but are difficult to diagnose accurately
Neutrophil gelatinase-associated lipocalin NGAL interleukin 1 Beta IL1beta and High Mobility Group AT-Hook 2 HmgA2 are molecules implicated in the process of inflammation and tumour development The diagnostic value of their concentration in pancreatic cysts is not established yet
Study aim to asses the significance of NGALIL1Beta and HMGA2 concentration in cystic fluid obtained by endoscopic ultrasound EUS with EUS-guided fine-needle aspiration EUS-FNA and serum level for discriminating between inflammatory and non-inflammatory pancreatic cyst
Pancreatic pseudocysts can be misdiagnosed as cystic neoplasms in particular when there is no clinical history of acute or chronic pancreatitis Pancreatic cystic neoplasms on the other hand are rare but are difficult to diagnose accurately
Neutrophil gelatinase-associated lipocalin NGAL interleukin 1 Beta IL1beta and High Mobility Group AT-Hook 2 HmgA2 are molecules implicated in the process of inflammation and tumour development The diagnostic value of their concentration in pancreatic cysts is not established yet
Study aim to asses the significance of NGALIL1Beta and HMGA2 concentration in cystic fluid obtained by endoscopic ultrasound EUS with EUS-guided fine-needle aspiration EUS-FNA and serum level for discriminating between inflammatory and non-inflammatory pancreatic cyst
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None