Ignite Creation Date:
2024-05-06 @ 6:09 PM
Last Modification Date:
2024-10-26 @ 2:43 PM
Study NCT ID:
NCT05568186
Status:
UNKNOWN
Last Update Posted:
2022-10-05
First Post:
2022-10-01
Brief Title:
Correlation Between Thermal Patterns of Infrared Thermal Imaging and Clinical Phenotype in Patients With Postherpetic Neuralgia
Sponsor:
Xianwei ZhangMD
Organization:
Huazhong University of Science and Technology
Study Overview
Official Title:
Correlation Between Different Thermal Patterns of Infrared Thermal Imaging and Clinical Phenotype and Prognosis in Patients With Postherpetic Neuralgia
Status:
UNKNOWN
Status Verified Date:
2022-10
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Postherpetic neuralgia PHN is the most frequent complication of herpes zosterHZ and is defined as pain persisting for 1month after the healing of herpetic skin lesion or pain persisting for 3 months following the onset of HZ PHN manifests as spontaneous throbbing stabbing or burning usually accompanied by various abnormal sensory symptoms which affect 5-20 of patients with HZ Due to the lack of accurate and objective auxiliary examination tools it is difficult for diagnosis and treatment of PHN As a non-invasive examination method infrared thermal imaging IRT can play a role in the diagnosis and treatment of neuropathic pain by objectively reflecting the changes and distribution characteristics of human body surface temperature However there are few studies on the relationship between clinical phenotype and thermal infrared image temperature changes in PHN patients and the relationship between the thermal pattern of skin temperature and the duration of disease and treatment progress in PHN patients has not been fully elucidated This study was conducted to investigate the relationship of thermal imaging data with the duration of the disease clinical phenotype treatment effect in order to explore the role of infrared thermal imaging in the diagnosis and treatment of PHN Methodsall PHN patients will included At each visit a pain NRS score was performed and clinical phenotypes were tested and labeled including allodynia numbness itching heat sensation cold sensation and the most painful areaMPA Infrared thermal imaging was performed the Average Relative Temperature ART within the affected area and the contralateral area was compared The relationship between the temperature change and duration of the disease clinical phenotype treatment effect was assessed
Detailed Description:
patients with the follow conditions were excluded 1The skin area was lesions because of other diseasetrauma inflammation skin scar skin disease tumor etc 2 history of psychiatric diseases chronic pain 3 inabilities to complete IRT examination
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None