Ignite Creation Date:
2024-05-06 @ 6:46 PM
Last Modification Date:
2024-10-26 @ 2:54 PM
Study NCT ID:
NCT05779813
Status:
RECRUITING
Last Update Posted:
2023-03-24
First Post:
2023-02-27
Brief Title:
Genetic Frontotemporal Dementia Initiative for Neurodevelopment
Sponsor:
Western University
Organization:
Western University
Study Overview
Official Title:
Genetic Frontotemporal Dementia Initiative for Neurodevelopment
Status:
RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
GENFI-NeuroDev
Brief Summary:
This is an international multi-centre cohort study of first and second degree family members of individuals who carry Frontotemporal Dementia FTD mutations in MAPT GRN or C9ORF72 repeat expansions for youths between the ages 9-17
Detailed Description:
GENFI-NeuroDev will study genetic FTD and its associated disorders including Motor Neurone Disease MNDAmyotrophic Lateral SclerosisALS in members of families with a known mutation in GRN or MAPT or an expansion in C9orf72 Participants with at-risk members of families first-degree and second-degree relatives of known genetic mutation carriers All GENFI-NeuroDev participants will be assessed longitudinally with a set of clinical neuropsychiatric cognitive imaging and biosample protocols Parents or guardians of potential GENFI NeuroDev participants are all aware of the autosomal dominant genetic nature of FTD in their family prior to being approached for potential participation in this study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None