Ignite Creation Date:
2024-05-05 @ 11:21 AM
Last Modification Date:
2024-10-26 @ 9:01 AM
Study NCT ID:
NCT00000541
Status:
COMPLETED
Last Update Posted:
2020-07-15
First Post:
1999-10-27
Brief Title:
Womens Antioxidant and Folic Acid Cardiovascular Study WAFACS
Sponsor:
Brigham and Womens Hospital
Organization:
Brigham and Womens Hospital
Study Overview
Official Title:
Womens Antioxidant and Folic Acid Cardiovascular Study WAFACS
Status:
COMPLETED
Status Verified Date:
2020-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
WAFACS
Brief Summary:
To determine if supplements of vitamin C vitamin E beta-carotene and B-vitamins a combination of folic acid vitamins B6 and B12 reduce risk of major cardiovascular events in high risk women with a prior history of atherosclerotic cardiovascular disease The trial is a companion to the Womens Health Study WHS a primary prevention trial of vitamin E and aspirin in a low risk population of women
Detailed Description:
The Womens Antioxidant and Folic Acid Cardiovascular Study tested the effects of vitamin C 500 mgday vitamin E 600 IU every other day andor beta carotene 50 mg every other day on the risk of major cardiovascular events a combined outcome of myocardial infarction stroke coronary revascularization or cardiovascular death among 8171 female health professionals at increased risk Participants were 40 years or older with a history of cardiovascular disease or 3 or more cardiovascular risk factors and were followed for an average duration of 94 years from 1995-1996 to 2005 In 1998 5442 of these participants were further randomized to the B-vitamin intervention a daily combination pill containing folic acid 25 mg vitamin B6 50 mg vitamin B12 1 mg and were followed for 73 years from April 1998 through July 2005
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL046959 | NIH | None | httpsreporternihgovquickSearchR01HL046959 |