Ignite Creation Date:
2024-05-06 @ 7:11 PM
Last Modification Date:
2024-10-26 @ 3:02 PM
Study NCT ID:
NCT05923411
Status:
COMPLETED
Last Update Posted:
2024-06-04
First Post:
2023-06-20
Brief Title:
A Study for Multiple Tablet Forms of The Study Medicine PF-07220060 in Healthy Adults
Sponsor:
Pfizer
Organization:
Pfizer
Study Overview
Official Title:
A PHASE 1 RANDOMIZED OPEN-LABEL PARALLEL-GROUP SINGLE-DOSE STUDY IN HEALTHY PARTICIPANTS TO INVESTIGATE THE RELATIVE BIOAVAILABILITY OF TWO TABLET FORMULATIONS OF PF-07220060 AND TO INVESTIGATE THE EFFECT OF FOOD AND A PROTON PUMP INHIBITOR ON THE RELATIVE BIOAVAILABILITY OF PF-07220060
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to compare multiple formulations of PF-07220060 in terms of their uptake into the blood stream The study will assess the effects of food and Rabeprazole on the uptake of PF-07220060 Rabeprazole belongs to a type of medications called proton pump inhibitors In reality some patients may take both PF-07220060 and rabeprazole together
This study is seeking participants that are
- Healthy male or female aged 18 to 65 years
Participants in this study will receive PF-07220060 once or twice by mouth The participants may receive different tablets for PF-07220060 Some participants will take a meal before receiving PF-07220060 In addition some participants will take rabeprazole by mouth for 7 days before taking PF-07220060
The study will compare experiences of people receiving different formulations of PF-07220060 Experiences of people taking food and rabeprazole with PF-07220060 will be compared to those on PF-07220060 alone This will help understand how much PF-07220060 is taken up into the blood It will also help understand how meal and Rabeprazole medicine changes the uptake of PF-07220060 into the blood
Participants will take part in the study for a maximum of 74 days During this time they will have to stay onsite for 5 to 13 days There will be up to 2 onsite study visits
This study is seeking participants that are
- Healthy male or female aged 18 to 65 years
Participants in this study will receive PF-07220060 once or twice by mouth The participants may receive different tablets for PF-07220060 Some participants will take a meal before receiving PF-07220060 In addition some participants will take rabeprazole by mouth for 7 days before taking PF-07220060
The study will compare experiences of people receiving different formulations of PF-07220060 Experiences of people taking food and rabeprazole with PF-07220060 will be compared to those on PF-07220060 alone This will help understand how much PF-07220060 is taken up into the blood It will also help understand how meal and Rabeprazole medicine changes the uptake of PF-07220060 into the blood
Participants will take part in the study for a maximum of 74 days During this time they will have to stay onsite for 5 to 13 days There will be up to 2 onsite study visits
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None