Ignite Creation Date:
2024-05-05 @ 11:21 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00006315
Status:
COMPLETED
Last Update Posted:
2016-05-13
First Post:
2000-09-28
Brief Title:
DoseResponse of Exercise on Long Term Weight Loss
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2005-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To examine the dose-response of exercise on long-term weight loss in overweight adult women
Detailed Description:
BACKGROUND
Exercise is a key component of behavioral weight loss programs because of its effect on weight loss body composition cardiovascular disease risk factors and other obesity related diseases such as type 2 diabetes mellitus Despite these benefits it is unclear whether there is an optimal exercise duration andor intensity that will enhance long-term weight loss The current public health recommendation for physical activity is for individuals to participate in at least 30 minutes of moderate intensity physical activity on most days of the week approximately 150 minutes per week total However it is unclear whether this amount of exercise is adequate for long-term weight loss Moreover cross-sectional studies have shown that individuals that have been successful at long-term weight loss participate in levels of physical activity that are greater than the current public health recommendations
DESIGN NARRATIVE
The researchers hypothesized that adopting higher levels of exercise duration andor intensity coupled with a strong behavioral intervention would enhance long-term weight loss To test this hypothesis they recruited 200 overweight women and randomly assigned them to one of four treatment groups 1 moderate intensity moderate 1000calwk duration exercise 2 vigorous intensity moderate duration exercise 3 moderate 2000calwk intensity high duration exercise and 4 vigorous intensity high duration exercise All subjects participated in a 24-month behavioral weight loss program with subjects attending group meetings and receiving periodic telephone contacts from the weight loss program with subjects attending group meetings and receiving periodic telephone contacts from the interventionists In addition to facilitate the adoption of the exercise protocols all subjects were provided with a home treadmill Assessment of body weight occured at 0 6 12 and 24 months and exercise participation was measured throughout the program In addition body composition cardiorespiratory fitness cardiovascular disease risk factors and mediators of behavior change were measured at 0 6 12 and 24 months
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Exercise is a key component of behavioral weight loss programs because of its effect on weight loss body composition cardiovascular disease risk factors and other obesity related diseases such as type 2 diabetes mellitus Despite these benefits it is unclear whether there is an optimal exercise duration andor intensity that will enhance long-term weight loss The current public health recommendation for physical activity is for individuals to participate in at least 30 minutes of moderate intensity physical activity on most days of the week approximately 150 minutes per week total However it is unclear whether this amount of exercise is adequate for long-term weight loss Moreover cross-sectional studies have shown that individuals that have been successful at long-term weight loss participate in levels of physical activity that are greater than the current public health recommendations
DESIGN NARRATIVE
The researchers hypothesized that adopting higher levels of exercise duration andor intensity coupled with a strong behavioral intervention would enhance long-term weight loss To test this hypothesis they recruited 200 overweight women and randomly assigned them to one of four treatment groups 1 moderate intensity moderate 1000calwk duration exercise 2 vigorous intensity moderate duration exercise 3 moderate 2000calwk intensity high duration exercise and 4 vigorous intensity high duration exercise All subjects participated in a 24-month behavioral weight loss program with subjects attending group meetings and receiving periodic telephone contacts from the weight loss program with subjects attending group meetings and receiving periodic telephone contacts from the interventionists In addition to facilitate the adoption of the exercise protocols all subjects were provided with a home treadmill Assessment of body weight occured at 0 6 12 and 24 months and exercise participation was measured throughout the program In addition body composition cardiorespiratory fitness cardiovascular disease risk factors and mediators of behavior change were measured at 0 6 12 and 24 months
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL064991 | NIH | None | httpsreporternihgovquickSearchR01HL064991 |