Ignite Creation Date:
2024-05-06 @ 7:42 PM
Last Modification Date:
2024-10-26 @ 3:12 PM
Study NCT ID:
NCT06104540
Status:
RECRUITING
Last Update Posted:
2024-02-01
First Post:
2023-10-23
Brief Title:
Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns
Sponsor:
Ankara Yildirim Beyazıt University
Organization:
Ankara Yildirim Beyazıt University
Study Overview
Official Title:
Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Pain itching hypertrophic scar formation after wound healing in burn patients complications sleep disturbances in patients anxiety depression and daily life It may disrupt activities and deterioration in quality of life Liquid petroleum jelly and olive oil have no side effects moisturizing properties or wound-healing treatment of burns due to their positive effects on symptoms such as itching can be used to alleviate burns The project found the use of liquid petroleum jelly and olive oil to determine the effect on itching and scarring in burn patients After burns reduction of symptoms such as itching dryness hypertrophic scarring and patient comfort Provision of care is a part of nursing care In studies itching and scarring there is insufficient evidence regarding the treatment methods applied for its treatment is observed In addition the effect of olive oil and liquid petroleum jelly on itching and scarring no scientific study was found The results of the project were found to be significant in terms of post-burn itching providing evidence of hypertrophic scar management and contributing to ongoing studies is expected to be found Since there are no similar studies in the literature a preliminary study with 24 patient applications will be made In line with the data obtained from the pre-application the sample calculation will be made and the application will continue by making the necessary arrangements Patients will be divided into experimental and control groups by simple randomization All patient groups individual data collection forms on the first day 12 individual data collection forms on the first day 15th day first second and third months Itemized Itch Severity Scale Patient and Observer Scar Scale to be applied in Burn Patients and the wound area will be photographed Patients in the control group will be given no application will be made Liquid petroleum jelly and olive oil group before the study training will be given and they will massage the recommended product twice a day for 3 months and will be asked to record them The data obtained at the end of the project will be statistically analyzed and results will be presented
Detailed Description:
In addition to localized damage burn is defined as a comprehensive trauma that affects the whole organism and determines the prognosis with its physiological response and can cause physical psychological sociological and economic problems in the individual Although the etiology of burn injuries varies according to industrialization socioeconomic cultural educational and age groups scald burns flame burns and electrical burns are the most common causes of burn injuries Esen et al 2021 reported that scald burns ranked first among the causes of burns with 372 in their study Although survival in patients has increased with advances in burn treatment wound healing and understanding of scar pathophysiology burns are still an important cause of morbidity In these patients postburn pruritus and hypertrophic scarring is a common and important complication that occurs during the wound-healing process Histamine produced by mast cells during the injury process plays a role in the development of post-burn itching and acute itching begins with wound closure The prevalence of itching after burns is reported to be 80-100 The risk of itching increases in patients with large burn surface area surgical procedures related to burn hypertrophic scarring female gender dry skin limb and facial burns In addition to itching patients may experience various sensory disturbances such as pinprick stabbing or burning after burns
Another problem affecting patients after burns is the development of hypertrophic scarring Abnormal increase of collagen and glycoprotein and transepidermal water loss during the wound healing process can cause hypertrophic scarring or keloid In wound healing hypertrophic scarring occurs within four weeks after complete reepithelialization and regresses in approximately 15 months The incidence of hypertrophic scar formation following burn injuries ranges from 34 to 94 In one study itching pain and paresthesia requiring treatment were observed in patients with hypertrophic scarring and it is recommended to identify and prevent risk factors for treatment and symptom control
Alleviation of itching symptoms after burns and early diagnosis of hypertrophic scar development is important in rehabilitation Itching and hypertrophic scarring can cause cosmetic problems severe functional disability pain sleep disorders re-damage of fragile skin and risk of infection with microorganism colonization anxiety and depression Topical moisturizers cold application pressure garments antihistamines massage psychological therapy and dermatological treatments surgical techniques and laser treatment can be applied in the treatment The effectiveness of all these treatment methods is limited and there is insufficient evidence
One of the factors that make scars visible is dry skin due to transepidermal water loss and skin should be kept moist to minimize the appearance of scars The use of moisturizers has been identified as one of the components of treatment to reduce itching and hypertrophic scarring Moisturizers are available in the form of plant extracts and various oils Various topical products with moisturizing properties such as olive oil and St Johns wort can be used in the treatment of burns and alleviation of itching and dryness symptoms after burns due to their cheap and easy availability lack of side effects moisturizing properties positive properties on wound healing Olive oil contains fatty components such as oleic acid phenolic compounds chlorophyll and vitamin E These components accelerate wound healing moisturize the skin and provide elasticity to the skin In the study investigating the effect of olive oil and flaxseed on burn healing it was shown that when the oils were applied as a mixture they reduced inflammation and had a positive effect on wound size
One of the products used for moisturizing is liquid petroleum jelly Liquid petroleum jelly is obtained from liquid petroleum consisting of colorless odorless oily saturated hydrocarbons It is widely used for cosmetic purposes and is included in the composition of many topical products It reduces skin water loss moisturizes the skin reduces itching symptoms acts as a barrier and protects skin integrity Wang et al 2020 found that liquid petroleum jelly was more effective in wound healing and prevention of infection compared to normal saline in their research evaluating the effectiveness of liquid petroleum jelly in the treatment of burn wounds
Problems such as itching dryness scarring and hypertrophic scarring after burns negatively affect the patients quality of life and body image Therefore the nurse should know the treatment and preventive measures and evaluate the effectiveness of the interventions using appropriate measurement tools It is stated in the literature that the substances in the composition of olive oil support wound healing and moisturizing properties but there are no clinical studies investigating the effect of olive oil and liquid petroleum jelly on itching and scarring in burn wounds This study aims to determine the effect of topically applied olive oil and liquid petroleum jelly on itching and scarring in post-burn patients
Expected benefits and risks of research The study will be conducted to determine the effect of olive oil and liquid petroleum jelly on itching and scarring that occur during the healing period after a scald burn
This study aims to help patients cope with itching and scarring problems that occur in the post-burn period and to shed light on the nursing interventions to be made for a more qualified life
Another problem affecting patients after burns is the development of hypertrophic scarring Abnormal increase of collagen and glycoprotein and transepidermal water loss during the wound healing process can cause hypertrophic scarring or keloid In wound healing hypertrophic scarring occurs within four weeks after complete reepithelialization and regresses in approximately 15 months The incidence of hypertrophic scar formation following burn injuries ranges from 34 to 94 In one study itching pain and paresthesia requiring treatment were observed in patients with hypertrophic scarring and it is recommended to identify and prevent risk factors for treatment and symptom control
Alleviation of itching symptoms after burns and early diagnosis of hypertrophic scar development is important in rehabilitation Itching and hypertrophic scarring can cause cosmetic problems severe functional disability pain sleep disorders re-damage of fragile skin and risk of infection with microorganism colonization anxiety and depression Topical moisturizers cold application pressure garments antihistamines massage psychological therapy and dermatological treatments surgical techniques and laser treatment can be applied in the treatment The effectiveness of all these treatment methods is limited and there is insufficient evidence
One of the factors that make scars visible is dry skin due to transepidermal water loss and skin should be kept moist to minimize the appearance of scars The use of moisturizers has been identified as one of the components of treatment to reduce itching and hypertrophic scarring Moisturizers are available in the form of plant extracts and various oils Various topical products with moisturizing properties such as olive oil and St Johns wort can be used in the treatment of burns and alleviation of itching and dryness symptoms after burns due to their cheap and easy availability lack of side effects moisturizing properties positive properties on wound healing Olive oil contains fatty components such as oleic acid phenolic compounds chlorophyll and vitamin E These components accelerate wound healing moisturize the skin and provide elasticity to the skin In the study investigating the effect of olive oil and flaxseed on burn healing it was shown that when the oils were applied as a mixture they reduced inflammation and had a positive effect on wound size
One of the products used for moisturizing is liquid petroleum jelly Liquid petroleum jelly is obtained from liquid petroleum consisting of colorless odorless oily saturated hydrocarbons It is widely used for cosmetic purposes and is included in the composition of many topical products It reduces skin water loss moisturizes the skin reduces itching symptoms acts as a barrier and protects skin integrity Wang et al 2020 found that liquid petroleum jelly was more effective in wound healing and prevention of infection compared to normal saline in their research evaluating the effectiveness of liquid petroleum jelly in the treatment of burn wounds
Problems such as itching dryness scarring and hypertrophic scarring after burns negatively affect the patients quality of life and body image Therefore the nurse should know the treatment and preventive measures and evaluate the effectiveness of the interventions using appropriate measurement tools It is stated in the literature that the substances in the composition of olive oil support wound healing and moisturizing properties but there are no clinical studies investigating the effect of olive oil and liquid petroleum jelly on itching and scarring in burn wounds This study aims to determine the effect of topically applied olive oil and liquid petroleum jelly on itching and scarring in post-burn patients
Expected benefits and risks of research The study will be conducted to determine the effect of olive oil and liquid petroleum jelly on itching and scarring that occur during the healing period after a scald burn
This study aims to help patients cope with itching and scarring problems that occur in the post-burn period and to shed light on the nursing interventions to be made for a more qualified life
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None