Ignite Creation Date:
2024-05-06 @ 7:43 PM
Last Modification Date:
2024-10-26 @ 3:13 PM
Study NCT ID:
NCT06119854
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-05-07
First Post:
2023-11-03
Brief Title:
Brief Digital Intervention to Increase COVID-19 Vaccination Among Individuals With Anxiety or Depression
Sponsor:
City University of New York School of Public Health
Organization:
City University of New York School of Public Health
Study Overview
Official Title:
Brief Digital Intervention to Increase COVID-19 Vaccination Among Individuals With Anxiety or Depression
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The COVID-19 pandemic has led to a misdisinformation ecosystem that promotes divergent views of vaccine efficacy as well as the legitimacy of science and medicine Individuals are confronted with vaccine-related information from a multitude of sources posing a challenge to identifying inaccurate information COVID-19 vaccine uptake is lower among people with anxiety and depression than in the general population due in part to higher levels of vaccine hesitancy The prevalence of anxiety and depressive symptoms among US adults increased significantly during the COVID pandemic and has remained elevated Interventions capable of mitigating the impact of vaccine hesitancy and misdisinformation among undervaccinated people with anxiety or depression are therefore an urgent priority Emerging evidence suggests that reasons for vaccine hesitancy and the impact of conventional vaccination messaging differ between those with and without mental health symptoms There may also be added challenges overcoming logistical barriers to vaccination for people with anxiety or depressive symptoms
The investigators aim to determine the effectiveness of two different brief digital intervention strategies compared with conventional public health messaging for increasing vaccine uptake in undervaccinated adults with and without anxiety or depressive symptoms Attitudinal inoculation is a brief scalable strategy that leverages the power of narrative values and emotion to strengthen resistance to misdisinformation and reduce hesitancy Though this approach has been shown to decrease COVID-19 vaccine hesitancy among US adults the extent to which this approach increases COVID-19 vaccination remains unknown Cognitive-behavioral therapy CBT is an evidence-based intervention for anxiety and depression However the efficacy of incorporating CBT-informed messaging in a vaccine promotion intervention has not been tested The investigators hypothesize that both attitudinal inoculation and CBT-style communication will be more effective than conventional public health messaging to increase COVID-19 vaccination The investigators also hypothesize that the CBT-informed intervention will be more effective than the attitudinal inoculation intervention for increasing COVID-19 vaccination among participants with symptoms of anxiety or depression
The investigators aim to determine the effectiveness of two different brief digital intervention strategies compared with conventional public health messaging for increasing vaccine uptake in undervaccinated adults with and without anxiety or depressive symptoms Attitudinal inoculation is a brief scalable strategy that leverages the power of narrative values and emotion to strengthen resistance to misdisinformation and reduce hesitancy Though this approach has been shown to decrease COVID-19 vaccine hesitancy among US adults the extent to which this approach increases COVID-19 vaccination remains unknown Cognitive-behavioral therapy CBT is an evidence-based intervention for anxiety and depression However the efficacy of incorporating CBT-informed messaging in a vaccine promotion intervention has not been tested The investigators hypothesize that both attitudinal inoculation and CBT-style communication will be more effective than conventional public health messaging to increase COVID-19 vaccination The investigators also hypothesize that the CBT-informed intervention will be more effective than the attitudinal inoculation intervention for increasing COVID-19 vaccination among participants with symptoms of anxiety or depression
Detailed Description:
The project will recruit undervaccinated participants with and without symptoms of anxiety or depression from the CHASING COVID Cohort a large and geographically diverse community-based US cohort to tailor and test the effectiveness of two brief digital interventions to increase vaccine uptake among adults with anxiety or depressive symptoms The investigators will assign undervaccinated cohort participants with and without symptoms of anxiety or depression to 1 an attitudinal inoculation intervention 2 a CBT-informed intervention or 3 a conventional public health messaging intervention without attitudinal inoculation or CBT-informed content The investigators will examine the outcome of COVID-19 vaccination at 4 weeks post-intervention conducting intent-to-treat comparisons between arms
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None