Ignite Creation Date:
2024-05-06 @ 7:51 PM
Last Modification Date:
2024-10-26 @ 3:16 PM
Study NCT ID:
NCT06169917
Status:
RECRUITING
Last Update Posted:
2023-12-14
First Post:
2023-09-04
Brief Title:
Pain Processing In Relation To Breathing
Sponsor:
Balgrist University Hospital
Organization:
Balgrist University Hospital
Study Overview
Official Title:
Potential Influences of Respiration Patterns on Experimental Pain Sensitization
Status:
RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to investigate the effect of breathing on the processing of experimental pain in healthy participants The main questions are
1 Does breathing rate influence the spatial extent of thermally induced secondary hyperalgesia a proxy of central sensitization
2 Does resonance frequency breathing influence the autonomic nervous system compared to baseline and compared to paced breathing at a natural frequency
3 Is spinal excitability measured using the magnitude of the nociception withdrawal reflex NWR affected by resonance frequency breathing compared to paced breathing at a natural frequency
Participants
will receive heat stimuli
s skins sensitivity will be tested using quantitative sensory testing tools
will receive various instructions on the speed of their breathing
s heart rate respiratory rate and sweat response will be measured
will fill in questionnaires
Researchers will compare the spatial extent of sensitivity resulting from application of heat stimuli during paced resonance frequency breathing compared to paced breathing at a natural frequency to see if the breathing rhythm influences central sensitization processes
1 Does breathing rate influence the spatial extent of thermally induced secondary hyperalgesia a proxy of central sensitization
2 Does resonance frequency breathing influence the autonomic nervous system compared to baseline and compared to paced breathing at a natural frequency
3 Is spinal excitability measured using the magnitude of the nociception withdrawal reflex NWR affected by resonance frequency breathing compared to paced breathing at a natural frequency
Participants
will receive heat stimuli
s skins sensitivity will be tested using quantitative sensory testing tools
will receive various instructions on the speed of their breathing
s heart rate respiratory rate and sweat response will be measured
will fill in questionnaires
Researchers will compare the spatial extent of sensitivity resulting from application of heat stimuli during paced resonance frequency breathing compared to paced breathing at a natural frequency to see if the breathing rhythm influences central sensitization processes
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None