Ignite Creation Date:
2024-05-06 @ 7:54 PM
Last Modification Date:
2024-10-26 @ 3:16 PM
Study NCT ID:
NCT06177496
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-12-20
First Post:
2023-11-27
Brief Title:
Influence of Sarcopenia in Hepatocellular Carcinoma Patients
Sponsor:
Sohag University
Organization:
Sohag University
Study Overview
Official Title:
Influence of Sarcopenia on Mortality and Disease Progression in Hepatocellular Carcinoma Treated With Ablation Embolization and Sorafenib
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Liver cancer poses a major threat to the global cancer burden and the number of deaths is estimated to be more than one million annually by 2030 Locoregional therapies such as transarterial chemoembolization TACE transarterial radioembolization TARE and radiation are associated with improved survival and quality of life for patients with unresectable HCC Couri and Pillai 2019 However curative therapies or locoregional therapies are not applicable to approximately 50 of HCC cases who are diagnosed at an advanced stage and have progression with transarterial therapies Park et al 2015 For these patients sorafenib lenvatinib and atezolizumab combined with bevacizumab have been approved as the first-line systemic therapy Fan et al 2022
Sarcopenia is a progressive and generalized skeletal muscle disease characterized by accelerated loss of muscle mass and function Cruz-Jentoft and Sayer 2019 It has been associated with higher mortality among the general population and patients with cancer This study aims to assess the possible role of sarcopenia in predicting the outcome of HCC patients following a variety of treatments including local ablation TACE and sorafenib
Sarcopenia is a progressive and generalized skeletal muscle disease characterized by accelerated loss of muscle mass and function Cruz-Jentoft and Sayer 2019 It has been associated with higher mortality among the general population and patients with cancer This study aims to assess the possible role of sarcopenia in predicting the outcome of HCC patients following a variety of treatments including local ablation TACE and sorafenib
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None