Ignite Creation Date:
2024-05-06 @ 8:00 PM
Last Modification Date:
2024-10-26 @ 3:18 PM
Study NCT ID:
NCT06217029
Status:
RECRUITING
Last Update Posted:
2024-02-26
First Post:
2024-01-08
Brief Title:
Magnetic Resonance Imaging Study on Young and Middle-aged Patients With Cervical Spondylotic Pain
Sponsor:
First Affiliated Hospital Xian Jiaotong University
Organization:
First Affiliated Hospital Xian Jiaotong University
Study Overview
Official Title:
Applied Research on Young and Middle-aged Patients With Cervical Spondylotic Pain Using T2-mapping T1ρ and Diffusion Kurtosis Imaging
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MRI-CervPain
Brief Summary:
Cervical and shoulder pain in young adults is commonly caused by intervertebral disc degeneration bulge or herniation Disc degeneration includes the synthetic and degradative imbalance of myxoid matrix degeneration of annulus collagen and decrease of water content in nucleus pulposus A few patients with cervical degeneration had moderate to severe pain but there are no obvious abnormalities in the shape and signal of the disc with routine MRI which may be related to the early discal degeneration In most cases the pain could be relieved by non-surgical treatment due to mild decreased proteoglycan and slight abnormality of water diffusion but these changes cannot be clearly demonstrated by routine MRI Therefore it is necessary to rely on sensitive MRI techniques to reflect the abnormal microstructure in the nucleus pulposus and annulus fibrosus so as to assist the early detection of the main reason in patients with neck and shoulder pain and the evaluation of the efficacy of treatment
Detailed Description:
This is an observational longitudinal and single-center study Confirmed patients with cervical and shoulder pain will complete several clinical and imaging programs before and after 3 and 12 months of non-surgical treatment for exploring the main reason of the symptom and the imaging predictors of treatment effect in the disease The collected materials are listed below 1 3 times cervical MRI scans including T2-mapping T1ρ and DKI sequences 2 visual analog scale for pain assessment and disease duration Then the T2 value T1ρ and DKI derived parameters will be measured in the nucleus pulposus and annulus fibrosus
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None