Ignite Creation Date:
2024-05-05 @ 11:21 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001366
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Mapping the Areas of the Brain Associated With Language in Children With Epilepsy
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
MRI-Based Functional Language Mapping in Children With Epilepsy
Status:
COMPLETED
Status Verified Date:
2002-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Researchers are interested in studying if magnetic resonance imaging MRI is practical for locating the areas of the brain associated with language in children with epilepsy
When a region of the brain is active it uses more fuel in the form of oxygen and sugar glucose As the brain uses more fuel it produces more waste products carbon dioxide and water Blood carries fuel to the brain and waste products away from the brain As brain activity increases blood flow to and from the area of activity increases also
Patients participating in the study will be asked to perform tasks designed to test language skills while undergoing an MRI to detect areas of the brain using oxygen and receiving blood flow
When a region of the brain is active it uses more fuel in the form of oxygen and sugar glucose As the brain uses more fuel it produces more waste products carbon dioxide and water Blood carries fuel to the brain and waste products away from the brain As brain activity increases blood flow to and from the area of activity increases also
Patients participating in the study will be asked to perform tasks designed to test language skills while undergoing an MRI to detect areas of the brain using oxygen and receiving blood flow
Detailed Description:
We propose to study the feasibility of utilizing MRI to perform functional mapping of language cortex in children with epilepsy We will use 15 Tesla MRI to study cerebral blood flow and tissue oxygenation during cognitive activation tasks derived from previous adult studies
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 93-N-0191 | None | None | None |