Ignite Creation Date:
2024-05-06 @ 8:03 PM
Last Modification Date:
2024-10-26 @ 3:19 PM
Study NCT ID:
NCT06231160
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-01-30
First Post:
2023-12-24
Brief Title:
Clinical Comparative Study of Systematic Therapy Combined With MWA and Systematic Therapy for Pancreatic Cancer
Sponsor:
Chinese PLA General Hospital
Organization:
Chinese PLA General Hospital
Study Overview
Official Title:
Clinical Comparative Study of Systematic Therapy Combined With Microwave Ablation and Systematic Therapy for Pancreatic Cancer
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Pancreatic carcinoma PC is the deadliest malignant tumors worldwide Surgical resection is one of the most effective methods for the treatment of PC but the resectable rate is less than 20 among the patients with PCs and the recurrent and metastatic rate is more than 80 in two years after resection Ablation has been confirmed one of the most effective methods for solid tumors by recent twenty years and proven to be a radical treatment similar to the surgical resection for the clinical applications of hepatic and renal tumors at early clinical staging in the internationally guidelines The purpose is to explore the efficacy and safety of microwave ablation in the treatment of pancreatic cancer in combination with systematic therapy
Detailed Description:
Pancreatic carcinoma PC is the deadliest malignant tumors worldwide Surgical resection is one of the most effective methods for the treatment of PC but the resectable rate is less than 20 among the patients with PCs and the recurrent and metastatic rate is more than 80 in two years after resection Furthermore it is difficult to achieve tumoral complete responses by traditional therapies including chemotherapy radiotherapy and transarterial embolization Ablation has been confirmed one of the most effective methods for solid tumors by recent twenty years and proven to be a radical treatment similar to the surgical resection for the clinical applications of hepatic and renal tumors at early clinical staging in the internationally guidelines However the published clinical practices on the thermal ablation of PCs with large-scale cases are rare One of the most important reasons for this originates from the extreme complexity and difficult regulation of the temperature distribution in tumors during thermal ablation because of the own characteristics of PCs including highly invasive growth without tumoral capsules high proportion of the interstitial fiber tissue and the unusual blood perfusion because of extremely chaotic microvascular structures The purpose is to explore the efficacy and safety of microwave ablation in the treatment of pancreatic cancer in combination with systematic therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None