Ignite Creation Date:
2024-05-06 @ 8:05 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06248138
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-02-08
First Post:
2024-01-09
Brief Title:
Factors Related to the Progression of Non-target Coronary Lesions
Sponsor:
Mei Gao
Organization:
Qianfoshan Hospital
Study Overview
Official Title:
Factors Related to the Progression of Non-target Coronary Lesions
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to learn about correlation between traditional risk factors and emerging risk factors on the progression of non-target coronary lesions in patients with non-target lesions on at least two coronary angiographies at the First Affiliated Hospital of Shandong First Medical University The main question it aims to answer is what the correlation between emerging risk factors and progression of coronary non-target lesions and try to explore the powerful predictors of progression of coronary non-target lesions and cardiovascular events
Participants will be divided into two groups based on coronary angiography results
1 progress groupThere is at least one major coronary artery left main artery left anterior descending artery left circumflex artery or the right coronary artery had non-target lesions and the coronary artery stenosis rate reached the progressive level on follow-up angiography
2 Non-progress groups On repeat angiography the rate of coronary stenosis did not reach progressive levels
Participants will be divided into two groups based on coronary angiography results
1 progress groupThere is at least one major coronary artery left main artery left anterior descending artery left circumflex artery or the right coronary artery had non-target lesions and the coronary artery stenosis rate reached the progressive level on follow-up angiography
2 Non-progress groups On repeat angiography the rate of coronary stenosis did not reach progressive levels
Detailed Description:
The laboratory and auxiliary examination indexes of the study participants were collected prior to two coronary angiography CAG procedures encompassing blood cell counts glucose metabolism lipid metabolism renal function cardiac function inflammatory factors etc Quantitative flow fraction QFR was employed for assigning values to coronary artery images and analyzing lesion information including plaque progression and non-progression The correlation between conventional risk factors lipoproteina homocysteine and other emerging risk factors with the progression of non-target coronary lesions was analyzed furthermore the predictive value of emerging risk factors for non-target coronary lesion progression was evaluated
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None