Ignite Creation Date:
2024-05-05 @ 11:21 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001235
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Genetic Studies in Alzheimers Disease
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Biochemical and Genetic Studies in Familial Alzheimers Disease
Status:
COMPLETED
Status Verified Date:
2004-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Alzheimers disease is a condition marked by the deterioration of mental function The disease usually begins in late middle life and results in death in 5 to 10 years Patients with Alzheimers disease typically suffer from memory loss confusion and disorientation The condition has become a major medical and social problem in the United States because of the increasing number of people living beyond the age of 65 The actual cause of Alzheimers disease is unknown
Researchers believe that Alzheimers disease or at least a portion of cases may be an inherited condition As a result many new techniques have been developed to study the genetic causes of Alzheimers disease and other neurological disorders Many of these genetic techniques require blood samples and a family pedigree A pedigree is a chart similar to a family tree that shows a patients family history
The purpose of this study is to collect family and psychosocial information blood and biopsy samples from patients with neurological diseases their families and normal volunteers This information gathered will be used to learn more about diseases that affect the brain
Researchers believe that Alzheimers disease or at least a portion of cases may be an inherited condition As a result many new techniques have been developed to study the genetic causes of Alzheimers disease and other neurological disorders Many of these genetic techniques require blood samples and a family pedigree A pedigree is a chart similar to a family tree that shows a patients family history
The purpose of this study is to collect family and psychosocial information blood and biopsy samples from patients with neurological diseases their families and normal volunteers This information gathered will be used to learn more about diseases that affect the brain
Detailed Description:
This is a screening and follow-up Protocol Recent technological advances have facilitated the development of new approaches for investigating the underlying genetic basis of neurological disorders but genetic questions remain open and on going Application of many genetic techniques require a family pedigree and blood sample Peripheral blood lymphoblasts which are banked also serve as a renewable source for harvesting DNA which can be used for developing genetic markers in the future This study will allow collection of family and psychosocial information and blood specimens from patients with neurological diseases their families and normal control subjects
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 88-N-0029 | None | None | None |