Ignite Creation Date:
2024-05-06 @ 8:07 PM
Last Modification Date:
2024-10-26 @ 3:21 PM
Study NCT ID:
NCT06264687
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-02-20
First Post:
2024-02-09
Brief Title:
Hepcidin After Intravenous Iron Treatment
Sponsor:
Pierre-Alexandre Krayenbühl
Organization:
Hausarztpraxis Brauereistrasse
Study Overview
Official Title:
Serum Hepcidin Response After Intravenous Iron Therapy
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to investigate the hepcidin hormone response after intravenous iron administration
Detailed Description:
Intravenous iron is often administered when peroral iron is insufficient to correct iron-deficiency or not tolerated Few studies have shown a relationship between pretherapeutic serum hepcidin levels and response to intravenous iron infusion the lower the pre-infusion hepcidin level the fewer red blood cell concentrates were used to correct anaemia However there are no studies investigating hepcidin levels after intravenous iron supplementation Furthermore some studies showed an increase in hepcidin 24 hours after ingesting oral iron supplements impairing the iron uptake the next day However how long hepcidin is increased after intravenous iron administration is unknown Prolonged serum hepcidin concentrations after an iron infusion would reduce intestinal iron absorption and continued simultaneous oral iron therapy would be pointless
This study investigates whether and how serum hepcidin concentrations change after intravenous iron therapy Women with iron deficiency serum ferritin below 30ngml without anaemia hemoglobin 117gl receive 500mg iron Ferinject intravenously Serum hepcidin levels are measured before therapy day 0 2 days day 2 and 7 days day 7 after infusion
This study investigates whether and how serum hepcidin concentrations change after intravenous iron therapy Women with iron deficiency serum ferritin below 30ngml without anaemia hemoglobin 117gl receive 500mg iron Ferinject intravenously Serum hepcidin levels are measured before therapy day 0 2 days day 2 and 7 days day 7 after infusion
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None