Ignite Creation Date:
2024-05-06 @ 8:08 PM
Last Modification Date:
2024-10-26 @ 3:21 PM
Study NCT ID:
NCT06267118
Status:
RECRUITING
Last Update Posted:
2024-02-20
First Post:
2024-01-07
Brief Title:
Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis
Sponsor:
Combined Military Hospital Pakistan
Organization:
Combined Military Hospital Pakistan
Study Overview
Official Title:
A Randomized Controlled Trial on the Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis in Children
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
children
Brief Summary:
The goal of this clinical trial is to compare the efficacy of hypertonic saline nebulization with adrenaline nebulization in the treatment of acute bronchiolitis in children Main aim is to evaluate the following in both group of patients
1 Improvement in Wood-Downes clinical score WDF score in bronchiolitis
2 Length of Hospitalization
1 Improvement in Wood-Downes clinical score WDF score in bronchiolitis
2 Length of Hospitalization
Detailed Description:
This is a double-blind clinical trial that will include all admitted patients with acute bronchiolitis meeting inclusion criteria admitted in Pediatrics department Combined Military Hospital Nowshera Patients will be divided into two groups randomly Group I patients will be nebulized with drug adrenaline every 6 hours and group II patients will be nebulized with hypertonic saline every 6 hours After 24 hours and 48 hours of nebulization researchers will record WDF score by measuring respiratory rate heart rate chest retractions chest auscultation findings and SPO₂ levels All data will be recorded on a research Performa including length of hospital stay Data will be entered on SPSS to calculate results Independent sample t-test was used to measure the effect of two drugs on the length of hospital stay and improvement of respiratory score with a 95 confidence interval P value less than 005 will be considered as significant
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None