Ignite Creation Date:
2024-05-06 @ 8:09 PM
Last Modification Date:
2024-10-26 @ 3:21 PM
Study NCT ID:
NCT06270810
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-03-15
First Post:
2024-02-14
Brief Title:
Cardiometabolic Effects of Combined Aerobic Exercise and Non-Exercise Physical Activity
Sponsor:
Kastamonu University
Organization:
Kastamonu University
Study Overview
Official Title:
Cardiometabolic Effects of Increasing Non-Exercise Physical Activity Combined With Aerobic Exercise in Overweight Young Women
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to investigate whether increasing non-exercise physical activity combined with aerobic exercise in overweight young women is superior to performing aerobic exercise alone in terms of some cardiometabolic variables
The main question it aims to answer is
Do both increasing non-exercise physical activity and doing aerobic exercise add more beneficial cardiometabolic effects to performing aerobic exercise alone in overweight young women
To answer this question overweight young women will be randomly assigned to two different groups of this research Volunteers in one of the groups will do moderate-intensity aerobic training and the other group will increase their non-exercise physical activities in addition to moderate-intensity aerobic training Then researchers will compare two groups to see the differences in cardiometabolic variables
The main question it aims to answer is
Do both increasing non-exercise physical activity and doing aerobic exercise add more beneficial cardiometabolic effects to performing aerobic exercise alone in overweight young women
To answer this question overweight young women will be randomly assigned to two different groups of this research Volunteers in one of the groups will do moderate-intensity aerobic training and the other group will increase their non-exercise physical activities in addition to moderate-intensity aerobic training Then researchers will compare two groups to see the differences in cardiometabolic variables
Detailed Description:
According to objective and subjective measurements time spent sedentary varies between 25 hours and 10 hours approximately in European countries In America this time is 844 hours on average According to accelerometer data the average total sedentary time of university students is 982 hours per day Sedentary behaviour SB is associated with cardiometabolic risk markers and increased risk of cardiovascular disease independent of moderate and vigorous physical activity PA Replacing sedentary time with PA of any intensity including low-intensity reduces all-cause mortality
In terms of some cardiovascular risk variables eg high triglycerides glucose LDL cholesterol total cholesterol data are insufficient and conflicting on the superiority of increasing non-exercise PA in addition to aerobic exercise over aerobic exercise alone Additionally to our knowledge whether increasing non-exercise PA combined with aerobic exercise is superior to performing aerobic exercise alone in young overweight women with high sedentary time has not been investigated Therefore this study was planned to investigate whether reducing SB and increasing non-exercise PA combined with aerobic exercise in overweight young women between the ages of 18-35 is superior to performing aerobic exercise alone in terms of some cardiometabolic variables For this purpose overweight female individuals between the ages of 18-35 will be invited to the research Thirty-two female volunteers who meet the inclusion and exclusion criteria will be randomly assigned to two different groups of this research These groups will be as follows
Aerobic Exercise Group Participants in this group will do moderate-intensity aerobic training four days a week for 8 weeks
Aerobic Exercisenon-Exercise Physical Activity Group Participants in this group will reduce their sedentary time and increase non-exercise PA in addition to moderate-intensity aerobic training for four days a week for 8 weeks
PA and SB data of the participants in both groups will be monitored with a wrist worn accelerometer throughout the study At the beginning of the study 4 weeks after the beginning and at the end of 8 weeks participants will be evaluated in terms of the cardiometabolic variables These variables are fasting serum glucose triglyceride HDL cholesterol LDL cholesterol HbA1c systolic blood pressure diastolic blood pressure cardiorespiratory fitness body mass index waist and hip circumference and body fat percentage If there is a difference between the two group averages in terms of all variables and the group-time interactions test assumptions are met analysis will be made with two-way mixed analysis of variance ANOVA Since 3 measurements will be made over time pairwise differences in change over time will be analyzed with a post hoc Bonferroni test
In terms of some cardiovascular risk variables eg high triglycerides glucose LDL cholesterol total cholesterol data are insufficient and conflicting on the superiority of increasing non-exercise PA in addition to aerobic exercise over aerobic exercise alone Additionally to our knowledge whether increasing non-exercise PA combined with aerobic exercise is superior to performing aerobic exercise alone in young overweight women with high sedentary time has not been investigated Therefore this study was planned to investigate whether reducing SB and increasing non-exercise PA combined with aerobic exercise in overweight young women between the ages of 18-35 is superior to performing aerobic exercise alone in terms of some cardiometabolic variables For this purpose overweight female individuals between the ages of 18-35 will be invited to the research Thirty-two female volunteers who meet the inclusion and exclusion criteria will be randomly assigned to two different groups of this research These groups will be as follows
Aerobic Exercise Group Participants in this group will do moderate-intensity aerobic training four days a week for 8 weeks
Aerobic Exercisenon-Exercise Physical Activity Group Participants in this group will reduce their sedentary time and increase non-exercise PA in addition to moderate-intensity aerobic training for four days a week for 8 weeks
PA and SB data of the participants in both groups will be monitored with a wrist worn accelerometer throughout the study At the beginning of the study 4 weeks after the beginning and at the end of 8 weeks participants will be evaluated in terms of the cardiometabolic variables These variables are fasting serum glucose triglyceride HDL cholesterol LDL cholesterol HbA1c systolic blood pressure diastolic blood pressure cardiorespiratory fitness body mass index waist and hip circumference and body fat percentage If there is a difference between the two group averages in terms of all variables and the group-time interactions test assumptions are met analysis will be made with two-way mixed analysis of variance ANOVA Since 3 measurements will be made over time pairwise differences in change over time will be analyzed with a post hoc Bonferroni test
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None