Ignite Creation Date:
2024-05-06 @ 8:09 PM
Last Modification Date:
2024-10-26 @ 3:21 PM
Study NCT ID:
NCT06271915
Status:
RECRUITING
Last Update Posted:
2024-03-05
First Post:
2024-02-15
Brief Title:
Role of Cervical Spine Mobilization on Lateral Epicondylitis
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
Effect of Cervical Spine Mobilization With Movement on Lateral Epicondylitis A Randomized Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The studys primary goal is to examine the effectiveness of Mulligans technique in reducing hyperalgesia in lateral epicondylitis focusing on cervical spine while also investigating its influence on central sensitization in relation to lateral epicondylitis
Detailed Description:
Lateral epicondylitis LE also known as tennis elbow results from an overuse injury due to eccentric overload on the common extensor tendon particularly at the origin of the extensor carpi radialis brevis ECRB This condition is frequently triggered by repetitive strain during tasks involving repeated gripping and loaded wrist extension Lateral epicondylitis affects 1 to 3 of population especially in middle-aged people In addition patients with LE suffer from pain or burning on the common extensor origin of the forearm that may radiate into the upper arm or downward to the forearm The pain can be exacerbated with resisted wrist extension forearm supination and middle finger extension The initial approach to manage lateral epicondylitis involves conservative therapy including eccentric training stretching and local manual therapy
In individuals with lateral epicondylitis the experience of mechanical hyperalgesia characterized by increased pain sensitivity during cold application is indicative of potential central sensitization Central sensitization involves heightened reactivity of nociceptors within the central nervous system resulting in increased responsiveness to both normal and sub-threshold afferent input This heightened sensitivity also includes increased responsiveness to non-noxious stimuli and an elevated pain response triggered by stimuli originating outside the area of injury indicating an expanded receptive field Furthermore cervical dysfunction is observable in individuals with LE even in the absence of neck pain indicating the involvement of central sanitization The potential influence of cervical manual therapy on reducing mechanical hyperalgesia aligns with addressing central sensitization contributing to a comprehensive approach in managing pain and sensitivity associated with lateral epicondylitis
Its hypothesized that spinal manual therapy on the cervical spine is likely to yield positive short-term outcomes on pain-free grip and the pain threshold elicited by pressure over the lateral humeral epicondyle As the mechanism of manual techniques proves effective on mechanical neurophysiological and peripheral receptors while inducing supraspinal pain inhibition related with sympathoexcitation3 hypoalgesia could occur following the application of these techniques
Mulligans mobilization and SNAGS approach involves applying force and direction to the facet joint reaching the end range of motion This technique aims to restore the original position of cervical spine facet joint which possibly impacts the hyperalgesia frequently associated with lateral epicondylitis Moreover mobilization with movement induces biomechanical changes in the vertebrae affecting central processing It restrains pain mechanisms reduces neck dysfunction and improves neck disability
Notably previous studies investigated that they have indicated the need for further research to determine the effects of spinal manipulation on hypoalgesia Furthermore other study previously explored the effects of manual therapy on the thoracic spine concerning pain-free grip and sympathetic activity in patients with lateral epicondylitis producing favorable outcomes needing additional exploration when including the cervical spine
As such the main objective of this study is to evaluate Mulligans technique effectiveness in relieving mechanical and cold hyperalgesia in individuals with lateral epicondylitis with a specific emphasis on the cervical spine region Additionally the research aims to investigate the impact of Mulligans technique on central sensitization in the cervical spine and its influence on lateral epicondylitis
In individuals with lateral epicondylitis the experience of mechanical hyperalgesia characterized by increased pain sensitivity during cold application is indicative of potential central sensitization Central sensitization involves heightened reactivity of nociceptors within the central nervous system resulting in increased responsiveness to both normal and sub-threshold afferent input This heightened sensitivity also includes increased responsiveness to non-noxious stimuli and an elevated pain response triggered by stimuli originating outside the area of injury indicating an expanded receptive field Furthermore cervical dysfunction is observable in individuals with LE even in the absence of neck pain indicating the involvement of central sanitization The potential influence of cervical manual therapy on reducing mechanical hyperalgesia aligns with addressing central sensitization contributing to a comprehensive approach in managing pain and sensitivity associated with lateral epicondylitis
Its hypothesized that spinal manual therapy on the cervical spine is likely to yield positive short-term outcomes on pain-free grip and the pain threshold elicited by pressure over the lateral humeral epicondyle As the mechanism of manual techniques proves effective on mechanical neurophysiological and peripheral receptors while inducing supraspinal pain inhibition related with sympathoexcitation3 hypoalgesia could occur following the application of these techniques
Mulligans mobilization and SNAGS approach involves applying force and direction to the facet joint reaching the end range of motion This technique aims to restore the original position of cervical spine facet joint which possibly impacts the hyperalgesia frequently associated with lateral epicondylitis Moreover mobilization with movement induces biomechanical changes in the vertebrae affecting central processing It restrains pain mechanisms reduces neck dysfunction and improves neck disability
Notably previous studies investigated that they have indicated the need for further research to determine the effects of spinal manipulation on hypoalgesia Furthermore other study previously explored the effects of manual therapy on the thoracic spine concerning pain-free grip and sympathetic activity in patients with lateral epicondylitis producing favorable outcomes needing additional exploration when including the cervical spine
As such the main objective of this study is to evaluate Mulligans technique effectiveness in relieving mechanical and cold hyperalgesia in individuals with lateral epicondylitis with a specific emphasis on the cervical spine region Additionally the research aims to investigate the impact of Mulligans technique on central sensitization in the cervical spine and its influence on lateral epicondylitis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None