Ignite Creation Date:
2024-05-06 @ 8:09 PM
Last Modification Date:
2024-10-26 @ 3:21 PM
Study NCT ID:
NCT06277193
Status:
COMPLETED
Last Update Posted:
2024-02-26
First Post:
2024-02-10
Brief Title:
Investigation of the Relationship Between Sarcopenia and Balance Fear of Falling and Fall Risk in Older Female Patients
Sponsor:
Konya Beyhekim Training and Research Hospital
Organization:
Konya Beyhekim Training and Research Hospital
Study Overview
Official Title:
Investigation of the Relationship Between Sarcopenia and Balance Fear of Falling and Fall Risk in Older Female Patients
Status:
COMPLETED
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study study type cross-sectional aims to investigate the relationship of sarcopenia level with balance fear of falling and risk of falling in the elderly female population In the first stage 166 participants were divided into two groups sarcopenia and non-sarcopenia Afterwards they were categorized according to sarcopenia level probable sarcopenia group sarcopenia group severe sarcopenia group group without sarcopenia and comparisons were made between these subgroups Then they were evaluated with various scales and tests in terms of balance fear of falling and risk of falling
Detailed Description:
The world population is experiencing an aging trend accompanied by declines in fertility and mortality rates This aging process varies among countries and regions The aging of societies leads to an increase in health and socioeconomic problems Sarcopenia is just one of the problems that arise with aging
Sarcopenia is defined as a progressive syndrome associated with a general loss of muscle mass and strength leading to a decrease in physical function deterioration in quality of life and even adverse outcomes such as death Although sarcopenia is primarily defined as a syndrome associated with the elderly population it can also be observed in non-elderly individuals with other diseases or conditions Therefore due to its higher prevalence in the elderly population it can also be referred to as a geriatric syndrome
The prevalence of sarcopenia varies depending on the measurement methods used to assess muscle mass muscle strength and muscle performance as well as the population studied The frequency of sarcopenia can range from 8 to 40 in populations aged 60 and over Muscle mass decreases linearly in both men and women after the age of 40 These losses in muscle mass continue at a rate of 8 per decade up to the age of 70 and increase to 15 in the subsequent decades Total loss can reach up to 50 in the eighth decade
The etiology of sarcopenia is multifactorial Aging certain chronic diseases immobility sedentary lifestyle and nutritional deficiencies can contribute to sarcopenia While sarcopenia can sometimes be attributed to a single cause in most cases a single cause cannot be identified Sarcopenia can generally be classified into two main categories primary and secondary Primary sarcopenia is solely associated with the aging process while secondary sarcopenia develops due to one or more causes such as immobility comorbidities nutrition However it may not always be possible to make a clear distinction between primary and secondary sarcopenia
Various imaging methods such as computerized tomography CT magnetic resonance imaging MRI or dual-energy X-ray absorptiometry DEXA can be used to determine muscle mass in the diagnosis of sarcopenia while anthropometric measurements such as bioimpedance analysis or upper mid-arm circumference and calf circumference may also be applied Muscle strength is generally measured using a hand dynamometer while methods such as walking tests sit-to-stand tests or stair climbing tests can be used to assess muscle performance
Individuals who have results below critical values in muscle strength measurement but have normal muscle mass muscle quality and physical performance values are defined as probable sarcopenia If there is also low muscle mass in addition to decreased muscle strength this condition is classified as sarcopenia If there is a decrease in muscle mass or quality along with decreased muscle strength and physical performance this condition can be classified as severe sarcopenia
Balance is an expression of postural adaptation to changes in the center of gravity during rest or movement Factors that maintain balance are the integration of vestibular proprioceptive and visual data within the central nervous system and coordinated muscle activity resulting from voluntary or involuntary reflex activity Disruption of balance predisposes to falls A fall is a condition that usually results in an unwanted change in position without a significant intrinsic event strong external force or intentional movement usually on the ground or at a lower level It can also be defined as an uncorrectable change in position
One of the psychological consequences of falling is fear of falling This is defined as an anxiety condition that leads to avoidance of physical activity after a fall This condition is often accompanied by anxiety and loss of confidence Fear of falling may decrease over time or become continuous Previous fall events advanced age being female vision problems depressive mood polypharmacy and balance disorders can be among the risk factors for fear of falling
Studies have found that sarcopenia is associated with many diseases reduces quality of life increases dependency affects mortality and increases hospitalizations However studies investigating the relationship between balance risk of falling fear of falling and sarcopenia are limited in the literature This study aims to investigate the relationship between the level of sarcopenia and balance fear of falling and risk of falling in an elderly female population
Sarcopenia is defined as a progressive syndrome associated with a general loss of muscle mass and strength leading to a decrease in physical function deterioration in quality of life and even adverse outcomes such as death Although sarcopenia is primarily defined as a syndrome associated with the elderly population it can also be observed in non-elderly individuals with other diseases or conditions Therefore due to its higher prevalence in the elderly population it can also be referred to as a geriatric syndrome
The prevalence of sarcopenia varies depending on the measurement methods used to assess muscle mass muscle strength and muscle performance as well as the population studied The frequency of sarcopenia can range from 8 to 40 in populations aged 60 and over Muscle mass decreases linearly in both men and women after the age of 40 These losses in muscle mass continue at a rate of 8 per decade up to the age of 70 and increase to 15 in the subsequent decades Total loss can reach up to 50 in the eighth decade
The etiology of sarcopenia is multifactorial Aging certain chronic diseases immobility sedentary lifestyle and nutritional deficiencies can contribute to sarcopenia While sarcopenia can sometimes be attributed to a single cause in most cases a single cause cannot be identified Sarcopenia can generally be classified into two main categories primary and secondary Primary sarcopenia is solely associated with the aging process while secondary sarcopenia develops due to one or more causes such as immobility comorbidities nutrition However it may not always be possible to make a clear distinction between primary and secondary sarcopenia
Various imaging methods such as computerized tomography CT magnetic resonance imaging MRI or dual-energy X-ray absorptiometry DEXA can be used to determine muscle mass in the diagnosis of sarcopenia while anthropometric measurements such as bioimpedance analysis or upper mid-arm circumference and calf circumference may also be applied Muscle strength is generally measured using a hand dynamometer while methods such as walking tests sit-to-stand tests or stair climbing tests can be used to assess muscle performance
Individuals who have results below critical values in muscle strength measurement but have normal muscle mass muscle quality and physical performance values are defined as probable sarcopenia If there is also low muscle mass in addition to decreased muscle strength this condition is classified as sarcopenia If there is a decrease in muscle mass or quality along with decreased muscle strength and physical performance this condition can be classified as severe sarcopenia
Balance is an expression of postural adaptation to changes in the center of gravity during rest or movement Factors that maintain balance are the integration of vestibular proprioceptive and visual data within the central nervous system and coordinated muscle activity resulting from voluntary or involuntary reflex activity Disruption of balance predisposes to falls A fall is a condition that usually results in an unwanted change in position without a significant intrinsic event strong external force or intentional movement usually on the ground or at a lower level It can also be defined as an uncorrectable change in position
One of the psychological consequences of falling is fear of falling This is defined as an anxiety condition that leads to avoidance of physical activity after a fall This condition is often accompanied by anxiety and loss of confidence Fear of falling may decrease over time or become continuous Previous fall events advanced age being female vision problems depressive mood polypharmacy and balance disorders can be among the risk factors for fear of falling
Studies have found that sarcopenia is associated with many diseases reduces quality of life increases dependency affects mortality and increases hospitalizations However studies investigating the relationship between balance risk of falling fear of falling and sarcopenia are limited in the literature This study aims to investigate the relationship between the level of sarcopenia and balance fear of falling and risk of falling in an elderly female population
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None