Ignite Creation Date:
2024-05-06 @ 8:10 PM
Last Modification Date:
2024-10-26 @ 3:21 PM
Study NCT ID:
NCT06271408
Status:
RECRUITING
Last Update Posted:
2024-02-21
First Post:
2024-02-14
Brief Title:
Comparison of Bronchodilator Response From Three Different Aerosol Delivery Methods in Patients With COPD Using Hyperpolarized Xe 129 MRI Ventilation Imaging
Sponsor:
Polarean Inc
Organization:
Polarean Inc
Study Overview
Official Title:
Xenon Xe 129 Hyperpolarized MRI Ventilation Imaging for the Evaluation of Treatment Response Comparing Three Different Bronchodilator Aerosol Delivery Methods in Patients With COPD A Pilot Study
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to compare responses to bronchodilator treatment delivered by three different aerosol delivery methods in patients with chronic obstructive pulmonary disease COPD The main question it aims to answer is whether there are differences in lung ventilation following treatment with each of the three methods as measured using hyperpolarized Xe 129 with MRI
Participants will
Receive a standard dose of albuterol delivered using each of 3 aerosol delivery devices In total participants will receive three treatments separated by at least 1 week each
Following each treatment participants will have inhale an MRI contrast agent called hyperpolarized Xe 129 and will have images of their lungs taken with an MRI
Researchers will compare the different lung images taken after each treatment to see if there are differences in the distribution of air in the lungs known as ventilation
Participants will
Receive a standard dose of albuterol delivered using each of 3 aerosol delivery devices In total participants will receive three treatments separated by at least 1 week each
Following each treatment participants will have inhale an MRI contrast agent called hyperpolarized Xe 129 and will have images of their lungs taken with an MRI
Researchers will compare the different lung images taken after each treatment to see if there are differences in the distribution of air in the lungs known as ventilation
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None