Ignite Creation Date:
2024-05-06 @ 8:10 PM
Last Modification Date:
2024-10-26 @ 3:21 PM
Study NCT ID:
NCT06276335
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-03-08
First Post:
2024-02-16
Brief Title:
Influence of Timing of Implant Placement on Early Healing Molecular Events
Sponsor:
Queen Mary University of London
Organization:
Queen Mary University of London
Study Overview
Official Title:
Influence of Timing of Implant Placement on Early Healing Molecular Events A Two-centre Parallel Group Pilot Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Dental implants have been on the market for several years and they are routinely used to replace singlemultiple missing teeth with a high success rate However there is still a limited number of studies comparing the influence of timing of implant placement on wound healing In addition there is no data available on the signaling pathways and the expression of healing biomarkers involved in the early stages of osseointegration after immediate implant placement IP or delayed implant placement DP
The primary objective of this study is to describe changes in the expression of inflammatory angiogenesis and osseous biomarkers of saliva at 1 3 7 15 and 30 days and of PICF at 3 7 15 and 30 days after immediate implant placement IP compared with delayed placement DP
The primary objective of this study is to describe changes in the expression of inflammatory angiogenesis and osseous biomarkers of saliva at 1 3 7 15 and 30 days and of PICF at 3 7 15 and 30 days after immediate implant placement IP compared with delayed placement DP
Detailed Description:
This is a two-centre prospective parallel-group pilot study which will consist of 10 to 11 visits over a minimum period of 16 months The study will take place at the Centre for Oral Clinical Research COCR at the Institute of Dentistry Barts and The London School of Medicine and Dentistry Queen Mary University of London main centre United Kingdom and at Clinic of Reconstructive Dentistry University of Zurich Zurich in accordance with local guidelines and procedures interventions detailed below
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None