Ignite Creation Date:
2024-05-06 @ 8:10 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06287138
Status:
RECRUITING
Last Update Posted:
2024-02-29
First Post:
2023-12-11
Brief Title:
The Effect of Ciprofol on Breathing Patterns Respiratory Drive and Inspiratory Effort in Mechanically Ventilated Patients
Sponsor:
Capital Medical University
Organization:
Capital Medical University
Study Overview
Official Title:
The Effect of Ciprofol on Breathing Patterns Respiratory Drive and Inspiratory Effort in Mechanically Ventilated Patients
Status:
RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Sedatives and analgesics are usually given for analgesic anxiolytic or sedating purposes for patients with critical illness while they inevitably inhibit respiratory and circulatory function Sometimes patients receive deep sedation to induce hypoventilation or suppress spontaneous respiratory effort The sedation level in clinical practice is usually assessed with subjective sedation scoring systems such as the Richmond Agitation Sedation Scale RASS However studies have found that sedation depth based on RASS is not a reliable marker of respiratory drive during critical illness In recent years researchers have proposed to monitor the effects of sedatives and analgesics on respiratory indicators and to implement lung-protective sedation such as P01 Pocc Pmus WOB and PTP However different pharmacological characteristics different depths of sedation and different sedation regimens among different sedatives and analgesics make a great difference in their effects on respiration Ciprofol is an analog of propofol with increased stereoselective effects adding to its anesthetic properties is increasingly used in the intensive care unit but its effects on respiration are not well understood Therefore this study aims to investigate the effects of ciprofol on respiratory patterns respiratory drive and inspiratory effort in mechanically ventilated patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None