Ignite Creation Date:
2024-05-06 @ 8:10 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06287476
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-03-01
First Post:
2024-02-12
Brief Title:
Alveolar-capillary Reserve After Exercise in Chronic Obstructive Pulmonary Disease COPD COP-DTPA
Sponsor:
Rigshospitalet Denmark
Organization:
Rigshospitalet Denmark
Study Overview
Official Title:
Alveolar-capillary Reserve After Exercise in COPD
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
It is unknown whether individuals with COPD exhibit abnormal alveolar-capillary breaching during exercise and whether this contributes to exertional dyspnoea The aim of this study is to investigate whether individuals with COPD exhibit an abnormal increase in alveolar-capillary breaching during exertion as indicated by an increase alveolar-capillary permeability with a concomitantly exacerbated increase in lung tissue mass
Detailed Description:
It is unknown whether individuals with COPD exhibit abnormal alveolar-capillary breaching during exercise and whether this contributes to exertional dyspnoea The aim of this study is to investigate whether individuals with COPD exhibit an abnormal increase in alveolar-capillary breaching during exertion as indicated by an increase alveolar-capillary permeability with a concomitantly exacerbated increase in lung tissue mass The study participants include a control group and a group with COPD GOLD I-III Participants are undergoing three study days 1 Measurement of maximal aerobic capacity and lung function test 2 lung tissue mass and alveolar-capillary permeability is measured at rest and again 2 hours later immediately after the participant has exercised on a bicycle ergometer and 3 supine cardiac output and pulmonary capillary blood volume will be measured at rest and immediately after exercise
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None